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One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
Haoyi Wang et al.
CELL (2013)
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
Lei S. Qi et al.
CELL (2013)
One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
Hui Yang et al.
CELL (2013)
Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
Baohui Chen et al.
CELL (2013)
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
F. Ann Ran et al.
CELL (2013)
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert et al.
CELL (2013)
Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system
Albert W. Cheng et al.
CELL RESEARCH (2013)
Processing-Independent CRISPR RNAs Limit Natural Transformation in Neisseria meningitidis
Yan Zhang et al.
MOLECULAR CELL (2013)
A CRISPR/Cas system mediates bacterial innate immune evasion and virulence
Timothy R. Sampson et al.
NATURE (2013)
DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
NATURE BIOTECHNOLOGY (2013)
RNA-guided gene activation by CRISPR-Cas9-based transcription factors
Pablo Perez-Pinera et al.
NATURE METHODS (2013)
CRISPR RNA-guided activation of endogenous human genes
Morgan L. Maeder et al.
NATURE METHODS (2013)
Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
Kevin M. Esvelt et al.
NATURE METHODS (2013)
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
Matthew H. Larson et al.
NATURE PROTOCOLS (2013)
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
Chromosomal deletions and inversions mediated by TALENs and CRISPR/Cas in zebrafish
An Xiao et al.
NUCLEIC ACIDS RESEARCH (2013)
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
Zhonggang Hou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
Tunable and Multifunctional Eukaryotic Transcription Factors Based on CRISPR/Cas
Fahim Farzadfard et al.
ACS SYNTHETIC BIOLOGY (2013)
CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3
Edze R. Westra et al.
MOLECULAR CELL (2012)
Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli
Ido Yosef et al.
NUCLEIC ACIDS RESEARCH (2012)
In Vivo Protein Interactions and Complex Formation in the Pectobacterium atrosepticum Subtype I-F CRISPR/Cas System
Corinna Richter et al.
PLOS ONE (2012)
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
Giedrius Gasiunas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system
Tomas Sinkunas et al.
EMBO JOURNAL (2011)
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
Elitza Deltcheva et al.
NATURE (2011)
Structural basis for CRISPR RNA-guided DNA recognition by Cascade
Matthijs M. Jore et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions
Blake Wiedenheft et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Functions and Regulation of RNA Editing by ADAR Deaminases
Kazuko Nishikura
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
Josiane E. Garneau et al.
NATURE (2010)
Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease
Rachel E. Haurwitz et al.
SCIENCE (2010)
Short motif sequences determine the targets of the prokaryotic CRISPR defence system
F. J. M. Mojica et al.
MICROBIOLOGY-SGM (2009)
Phage response to CRISPR-Encoded resistance in Streptococcus thermophilus
Helene Deveau et al.
JOURNAL OF BACTERIOLOGY (2008)
CRISPR provides acquired resistance against viruses in prokaryotes
Rodolphe Barrangou et al.
SCIENCE (2007)