Nanocomposites consisting of copper and copper oxide incorporated into MoS4 nanostructures for sensitive voltammetric determination of bisphenol A

A nanocomposite (NC) of type Cu/Cu2O/CuO@MoS4 was obtained via coprecipitation and ahydrothermal approach from copper oxide nanoparticles and MoS4 nanostructures. A series of nanocomposites has been fabricated with varying fractions of MoS4. The NCs were characterized by XRD, XPS, SEM and TEM. The synergistic effect of enlarged specific surface, high electrocatalytic activity and the presence of mixed valencies strongly enhance the redox response at the interface of a glassy carbon electrode (GCE) modified with the NC. The intercalation properties of MoS4 in the NCs result in outstanding electro-oxidative performance towards bisphenol A (BPA). The modified GCE, best operated at +0.16V vs. SCE, has a linear response in the 0.0001M to 17M BPA concentration range (R-2=0.998) and high sensitivity (1587mAM(-1)cm(-2)). The sensor can detect BPA with very good selectivity, enhanced storage stability and a low detection limit of 0.10nM (S/N=3). This is the lowest value among the non-enzymatic biosensors reported until now. The sensor was used for real-time in-vitro monitoring of BPA in (spiked) serum samples.