相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Assessment of Tumor Redox Status through (S)-4-(3-[18F] fluoropropyl)-L-Glutamic Acid PET Imaging of System xc- Activity
Patrick N. McCormick et al.
CANCER RESEARCH (2019)
Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography
Hannah E. Greenwood et al.
CLINICAL CANCER RESEARCH (2019)
Cancer-associated fibroblasts modify lung cancer metabolism involving ROS and TGF-β signaling
Alberto Cruz-Bermudez et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Pharmacological targeting of mitochondria in cancer stem cells: An ancient organelle at the crossroad of novel anti-cancer therapies
Jan Skoda et al.
PHARMACOLOGICAL RESEARCH (2019)
Molecular genetics and cellular events of K-Ras-driven tumorigenesis
G. G. Jinesh et al.
ONCOGENE (2018)
Prognostic implications of 62Cu-diacetyl-bis (N 4-methylthiosemicarbazone) PET/CT in patients with glioma
Akira Toriihara et al.
ANNALS OF NUCLEAR MEDICINE (2018)
Celecoxib inhibits mitochondrial O2 consumption, promoting ROS dependent death of murine and human metastatic cancer cells via the apoptotic signalling pathway
Rhys Pritchard et al.
BIOCHEMICAL PHARMACOLOGY (2018)
The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy
Eunae Sandra Cho et al.
BIOMOLECULES & THERAPEUTICS (2018)
Selenocysteine in mammalian thioredoxin reductase and application of ebselen as a therapeutic
Xiaoyuan Ren et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
Significance of the mitochondrial thioredoxin reductase in cancer cells: An update on role, targets and inhibitors
Valeria Scalcon et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
Energy Metabolism Drugs Block Triple Negative Breast Metastatic Cancer Cell Phenotype
Silvia Cecilia Pacheco-Velazquez et al.
MOLECULAR PHARMACEUTICS (2018)
Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy
William C. Stafford et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Multiple Administrations of 64Cu-ATSM as a Novel Therapeutic Option for Glioblastoma: a Translational Study Using Mice with Xenografts
Yukie Yoshii et al.
TRANSLATIONAL ONCOLOGY (2018)
Elimination of stem-like cancer cell side-population by auranofin through modulation of ROS and glycolysis
Guo-Xin Hou et al.
CELL DEATH & DISEASE (2018)
Consumption of NADPH for 2-HG Synthesis Increases Pentose Phosphate Pathway Flux and Sensitizes Cells to Oxidative Stress
Susan J. Gelman et al.
CELL REPORTS (2018)
Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin - Thioredoxin system. 1. Understanding commonalities and differences among cell types
Gianluca Selvaggio et al.
REDOX BIOLOGY (2018)
Circadian and Metabolic Perspectives in the Role Played by NADPH in Cancer
Isabel Mendez et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
The role of cellular reactive oxygen species in cancer chemotherapy
Haotian Yang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Therapy-induced enrichment of cancer stem-like cells in solid human tumors: Where do we stand?
Sara R. Martins-Neves et al.
PHARMACOLOGICAL RESEARCH (2018)
Intermittent hypoxia promotes melanoma lung metastasis via oxidative stress and inflammation responses in a mouse model of obstructive sleep apnea
Lian Li et al.
RESPIRATORY RESEARCH (2018)
Reactive Oxygen Species: A Key Constituent in Cancer Survival
Seema Kumari et al.
BIOMARKER INSIGHTS (2018)
A Quantitative Chemoproteomic Platform to Monitor Selenocysteine Reactivity within a Complex Proteome
Daniel W. Bak et al.
CELL CHEMICAL BIOLOGY (2018)
Oxygen and Glucose Levels in Cell Culture Media Determine Resveratrol's Effects on Growth, Hydrogen Peroxide Production, and Mitochondrial Dynamics
Joao Fonseca et al.
ANTIOXIDANTS (2018)
Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent
Edmund V. Capparelli et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Hypoglycemia Enhances Epithelial-Mesenchymal Transition and Invasiveness, and Restrains the Warburg Phenotype, in Hypoxic HeLa Cell Cultures and Microspheroids
Alvaro Marin-Hernandez et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2017)
Auranofin to prevent progression of pancreatic ductal adenocarcinoma.
Mayrim V. Rios Perez et al.
JOURNAL OF CLINICAL ONCOLOGY (2017)
18F-5-Fluoroaminosuberic Acid as a Potential Tracer to Gauge Oxidative Stress in Breast Cancer Models
Hua Yang et al.
JOURNAL OF NUCLEAR MEDICINE (2017)
Control of the NADPH supply for oxidative stress handling in cancer
Rafael Moreno-Sanchez et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure
Markus Dagnell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Oxygen availability and metabolic reprogramming in cancer
Hong Xie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
The role of succinate and ROS in reperfusion injury - A critical appraisal
Tatyana N. Andrienko et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2017)
NADPH Oxidases: Insights into Selected Functions and Mechanisms of Action in Cancer and Stem Cells
Magdalena Skonieczna et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)
Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production
Jeremy A. Meier et al.
SCIENCE SIGNALING (2017)
Cancer acidity: An ultimate frontier of tumor immune escape and a novel target of immunomodulation
Veronica Huber et al.
SEMINARS IN CANCER BIOLOGY (2017)
Mitochondrial ROS control of cancer
Maria del Pilar Sosa Idelchik et al.
SEMINARS IN CANCER BIOLOGY (2017)
Bax and Bak Pores: Are We Closing the Circle?
Katia Cosentino et al.
TRENDS IN CELL BIOLOGY (2017)
Targeting the Thioredoxin System for Cancer Therapy
Junmin Zhang et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2017)
Basal oxidative stress ratio of head and neck squamous cell carcinomas correlates with nodal metastatic spread in patients under therapy
D. Dequanter et al.
ONCOTARGETS AND THERAPY (2017)
Celecoxib targets breast cancer stem cells by inhibiting the synthesis of prostaglandin E2 and down-regulating the Wnt pathway activity
Chaolin Huang et al.
ONCOTARGET (2017)
Increased reactive oxygen species levels cause ER stress and cytotoxicity in andrographolide treated colon cancer cells
Aditi Banerjee et al.
ONCOTARGET (2017)
NADPH accumulation is responsible for apoptosis in breast cancer cells induced by fatty acid synthase inhibition
Yanfen Cui et al.
ONCOTARGET (2017)
Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production
Jeremy A. Meier et al.
SCIENCE SIGNALING (2017)
Emerging Role of the Pentose Phosphate Pathway in Hepatocellular Carcinoma
Marta Anna Kowalik et al.
FRONTIERS IN ONCOLOGY (2017)
The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells
Ionica Masgras et al.
FRONTIERS IN ONCOLOGY (2017)
Detoxification of Mitochondrial Oxidants and Apoptotic Signaling Are Facilitated by Thioredoxin-2 and Peroxiredoxin-3 during Hyperoxic Injury
Benjamin J. Forred et al.
PLOS ONE (2017)
Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability
Thomas Briston et al.
SCIENTIFIC REPORTS (2017)
The Risk of Major NSAID Toxicity with Celecoxib, Ibuprofen, or Naproxen: A Secondary Analysis of the PRECISION Trial
Daniel H. Solomon et al.
AMERICAN JOURNAL OF MEDICINE (2017)
Glutamine Addiction in Kidney Cancer Suppresses Oxidative Stress and Can Be Exploited for Real-Time Imaging
Omran Abu Aboud et al.
CANCER RESEARCH (2017)
Oxidant and anti-oxidant status in common brain tumors: Correlation to TP53 and human biliverdin reductase
Pinar Atukeren et al.
CLINICAL NEUROLOGY AND NEUROSURGERY (2017)
Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells
A. K. Mohamad Fairus et al.
BIOCHIMIE (2017)
Gold(I) NHC Complexes: Antiproliferative Activity, Cellular Uptake, Inhibition of Mammalian and Bacterial Thioredoxin Reductases, and Gram-Positive Directed Antibacterial Effects
Claudia Schmidt et al.
CHEMISTRY-A EUROPEAN JOURNAL (2017)
Understanding the cancer cell phenotype beyond the limitations of current omics analyses
Rafael Moreno-Sanchez et al.
FEBS JOURNAL (2016)
An international randomised trial of celecoxib versus celecoxib plus difluoromethylornithine in patients with familial adenomatous polyposis
Patrick M. Lynch et al.
GUT (2016)
Metabolism in cancer metastasis
Georg F. Weber
INTERNATIONAL JOURNAL OF CANCER (2016)
Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation
Geraldine De Preter et al.
ONCOTARGET (2016)
Investigation into the distinct subcellular effects of docosahexaenoic acid loaded low-density lipoprotein nanoparticles in normal and malignant murine liver cells
Lacy R. Moss et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2016)
Effect of isoorientin on intracellular antioxidant defence mechanisms in hepatoma and liver cell lines
Li Yuan et al.
BIOMEDICINE & PHARMACOTHERAPY (2016)
64Cu-ATSM therapy targets regions with activated DNA repair and enrichment of CD133+ cells in an HT-29 tumor model: Sensitization with a nucleic acid antimetabolite
Yukie Yoshii et al.
CANCER LETTERS (2016)
Ex Vivo Testing of Patient-Derived Xenografts Mirrors the Clinical Outcome of Patients with Pancreatic Ductal Adenocarcinoma
David Roife et al.
CLINICAL CANCER RESEARCH (2016)
Mitochondrial ROS regulation of proliferating cells
Lauren Diebold et al.
FREE RADICAL BIOLOGY AND MEDICINE (2016)
Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells
Dongzhu Duan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Celecoxib with or without zoledronic acid for hormone-naive prostate cancer: Survival results from STAMPEDE (NCT00268476)
Nicholas D. James et al.
JOURNAL OF CLINICAL ONCOLOGY (2016)
X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action
Derek Parsonage et al.
JOURNAL OF STRUCTURAL BIOLOGY (2016)
Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis
Steven E. Nissen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Cancer stem cells and chemoresistance: The smartest survives the raid
Jihe Zhao
PHARMACOLOGY & THERAPEUTICS (2016)
Assessment of the Tumor Redox Status in Head and Neck Cancer by 62Cu-ATSM PET
Tetsuya Tsujikawa et al.
PLOS ONE (2016)
Clinical Profile of Cyclooxygenase-2 Inhibitors in Treating Non-Small Cell Lung Cancer: A Meta-Analysis of Nine Randomized Clinical Trials
Yuan Yuan Zhou et al.
PLOS ONE (2016)
Elevation of Glucose 6-Phosphate Dehydrogenase Activity Induced by Amplified Insulin Response in Low Glutathione Levels in Rat Liver
Misako Taniguchi et al.
TheScientificWorldJOURNAL (2016)
ROS homeostasis and metabolism: a dangerous liason in cancer cells
E. Panieri et al.
CELL DEATH & DISEASE (2016)
Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism
Kinan Alhallak et al.
BIOMEDICAL OPTICS EXPRESS (2016)
Elevation of Glucose 6-Phosphate Dehydrogenase Activity Induced by Amplified Insulin Response in Low Glutathione Levels in Rat Liver
Misako Taniguchi et al.
Scientific World Journal (2016)
Mitochondrial Redox Signaling and Tumor Progression
Yuxin Chen et al.
CANCERS (2016)
Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State
Alessandra Folda et al.
SCIENTIFIC REPORTS (2016)
Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax
Aisha Shamas-Din et al.
BIOCHEMICAL JOURNAL (2015)
Increased reactive oxygen species production during reductive stress: The roles of mitochondrial glutathione and thioredoxin reductases
Paavo Korge et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2015)
The emerging role of Nrf2 in mitochondrial function
Albena T. Dinkova-Kostova et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Cardiolipin-Cytochrome c Complex: Switching Cytochrome c from an Electron-Transfer Shuttle to a Myoglobin- and a Peroxidase-like Heme-protein
Paolo Ascenzi et al.
IUBMB LIFE (2015)
MNADK, a Long-Awaited Human Mitochondrion-Localized NAD Kinase
Ren Zhang
JOURNAL OF CELLULAR PHYSIOLOGY (2015)
Selective Cytotoxic Effects of Low-Power Laser Irradiation on Human Oral Cancer Cells
Wei-Zhe Liang et al.
LASERS IN SURGERY AND MEDICINE (2015)
Acute Activation of Oxidative Pentose Phosphate Pathway as First-Line Response to Oxidative Stress in Human Skin Cells
Andreas Kuehne et al.
MOLECULAR CELL (2015)
Auranofin: Repurposing an Old Drug for a Golden New Age
Christine Roder et al.
DRUGS IN R&D (2015)
Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma
Giuseppe Lucarelli et al.
ONCOTARGET (2015)
Hitting the Bull's-Eye in Metastatic Cancers-NSAIDs Elevate ROS in Mitochondria, Inducing Malignant Cell Death
Stephen John Ralph et al.
PHARMACEUTICALS (2015)
62Cu-Diacetyl-Bis (N4-Methylthiosemicarbazone) PET in Human Gliomas: Comparative Study with [18F]Fluorodeoxyglucose and L-Methyl-[11C]Methionine PET
K. Tateishi et al.
AMERICAN JOURNAL OF NEURORADIOLOGY (2014)
Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia
Warren Fiskus et al.
CANCER RESEARCH (2014)
Mitochondrial Ca2+ influx targets cardiolipin to disintegrate respiratory chain complex II for cell death induction
M-S Hwang et al.
CELL DEATH AND DIFFERENTIATION (2014)
Novel signaling axis for ROS generation during K-Ras-induced cellular transformation
M-T Park et al.
CELL DEATH AND DIFFERENTIATION (2014)
Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation
M. Ogrunc et al.
CELL DEATH AND DIFFERENTIATION (2014)
Redox Regulation of Cancer Metastasis: Molecular Signaling and Therapeutic Opportunities
Wenyong Yang et al.
DRUG DEVELOPMENT RESEARCH (2014)
Modeling cancer glycolysis under hypoglycemia, and the role played by the differential expression of glycolytic isoforms
Alvaro Marin-Hernandez et al.
FEBS JOURNAL (2014)
The thioredoxin antioxidant system
Jun Lu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Gold drug auranofin could reduce neuroinflammation by inhibiting microglia cytotoxic secretions and primed respiratory burst
Jocelyn M. Madeira et al.
JOURNAL OF NEUROIMMUNOLOGY (2014)
Functional Imaging of Oxidative Stress with a Novel PET Imaging Agent, 18F-5-Fluoro-L- Aminosuberic Acid
Jack M. Webster et al.
JOURNAL OF NUCLEAR MEDICINE (2014)
Powerhouse down: Complex II dissociation in the respiratory chain
Ming-Shih Hwang et al.
MITOCHONDRION (2014)
Mitochondrial oxidative phosphorylation TRAP(1)ped in tumor cells
Andrea Rasola et al.
TRENDS IN CELL BIOLOGY (2014)
Enhancement of auranofin-induced lung cancer cell apoptosis by selenocystine, a natural inhibitor of TrxR1 in vitro and in vivo
C. Fan et al.
CELL DEATH & DISEASE (2014)
Inhibition of succinate dehydrogenase by the mitochondrial chaperone TRAP1 has anti-oxidant and anti-apoptotic effects on tumor cells
Giulia Guzzo et al.
ONCOTARGET (2014)
Resolution of oxidative stress by thioredoxin reductase: Cysteine versus selenocysteine
Brian Cunniff et al.
REDOX BIOLOGY (2014)
A phase II trial of maintenance ADAPT therapy targeting colon cancer stem cells in patients with metastatic colorectal cancer
Edward H. Lin et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Application of 62Cu-Diacetyl-Bis (N4-Methylthiosemicarbazone) PET Imaging to Predict Highly Malignant Tumor Grades and Hypoxia-Inducible Factor-1α Expression in Patients with Glioma
K. Tateishi et al.
AMERICAN JOURNAL OF NEURORADIOLOGY (2013)
Redox Imbalance and Biochemical Changes in Cancer
Tonia C. Jorgenson et al.
CANCER RESEARCH (2013)
Tissue Redox Activity as a Hallmark of Carcinogenesis: From Early to Terminal Stages of Cancer
Rumiana Bakalova et al.
CLINICAL CANCER RESEARCH (2013)
Molecular Pathways: Reactive Oxygen Species Homeostasis in Cancer Cells and Implications for Cancer Therapy
Veronique Nogueira et al.
CLINICAL CANCER RESEARCH (2013)
Tissue redox activity as a sensing platform for imaging of cancer based on nitroxide redox cycle
Zhivko Zhelev et al.
EUROPEAN JOURNAL OF CANCER (2013)
ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence
Ryo Kodama et al.
GENES TO CELLS (2013)
Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells
Shanshan Pei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Classification of mitocans, anti-cancer drugs acting on mitochondria
Jiri Neuzil et al.
MITOCHONDRION (2013)
PKCi Maintains a Tumor-initiating Cell Phenotype That Is Required for Ovarian Tumorigenesis
Yin Wang et al.
MOLECULAR CANCER RESEARCH (2013)
Drug Repurposing for Gastrointestinal Stromal Tumor
Ziyan Y. Pessetto et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Modulation of oxidative stress as an anticancer strategy
Chiara Gorrini et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Involvement of ERK-Nrf-2 Signaling in Ionizing Radiation Induced Cell Death in Normal and Tumor Cells
Raghavendra S. Patwardhan et al.
PLOS ONE (2013)
Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
Gregory LaMonte et al.
CANCER & METABOLISM (2013)
The stability and activity of respiratory Complex II is cardiolipin-dependent
Christine T. Schwall et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2012)
Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming
Yoichiro Mitsuishi et al.
CANCER CELL (2012)
BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment Implications for breast cancer prevention with antioxidant therapies
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2012)
ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence
U. Weyemi et al.
ONCOGENE (2012)
An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII
Paul S. Donnelly et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Five-Year Analysis of the Prevention of Colorectal Sporadic Adenomatous Polyps Trial
Nadir Arber et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2011)
Redox Control and Interplay Between p53 Isoforms: Roles in the Regulation of Basal p53 Levels, Cell Fate, and Senescence
Hind Hafsi et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Modulation of doxorubicin resistance by the glucose-6-phosphate dehydrogenase activity
Manuela Polimeni et al.
BIOCHEMICAL JOURNAL (2011)
Cancer cells metabolically fertilize the tumor microenvironment with hydrogen peroxide, driving the Warburg effect Implications for PET imaging of human tumors
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2011)
Specific disintegration of complex II succinate: ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction
A. Lemarie et al.
CELL DEATH AND DIFFERENTIATION (2011)
A study of the relative importance of the peroxiredoxin-, catalase-, and glutathione-dependent systems in neural peroxide metabolism
Pericles Arruda Mitozo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Structural Determinants of Discrimination of NAD+ from NADH in Yeast Mitochondrial NADH Kinase Pos5
Takuya Ando et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Thioredoxin Reductase-2 Is Essential for Keeping Low Levels of H2O2 Emission from Isolated Heart Mitochondria
Brian A. Stanley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Permeabilization of the Mitochondrial Outer Membrane by Bax/Truncated Bid (tBid) Proteins as Sensitized by Cardiolipin Hydroperoxide Translocation MECHANISTIC IMPLICATIONS FOR THE INTRINSIC PATHWAY OF OXIDATIVE APOPTOSIS
Witold Korytowski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Observation of Curative Efficacy and Prognosis Following Combination Chemotherapy with Celecoxib in the Treatment of Advanced Colorectal Cancer
C-H Jin et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2011)
Internal radiotherapy with copper-64-diacetyl-bis (N4-methylthiosemicarbazone) reduces CD133+ highly tumorigenic cells and metastatic ability of mouse colon carcinoma
Yukie Yoshii et al.
NUCLEAR MEDICINE AND BIOLOGY (2011)
Molecular imaging of tumor metabolism and apoptosis
U. Haberkorn et al.
ONCOGENE (2011)
Acidic Environment Leads to ROS-Induced MAPK Signaling in Cancer Cells
Anne Riemann et al.
PLOS ONE (2011)
Distinct Redox Profiles of Selected Human Prostate Carcinoma Cell Lines: Implications for Rational Design of Redox Therapy
Luksana Chaiswing et al.
Cancers (2011)
Mitochondrial respiratory chain involvement in peroxiredoxin 3 oxidation by phenethyl isothiocyanate and auranofin
Kristin K. Brown et al.
FEBS LETTERS (2010)
HIF-1α signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells
Viktor Malec et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
The Selenium-independent Inherent Pro-oxidant NADPH Oxidase Activity of Mammalian Thioredoxin Reductase and Its Selenium-dependent Direct Peroxidase Activities
Qing Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
Johanna Chiche et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)
Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger
Stephen J. Ralph et al.
MOLECULAR ASPECTS OF MEDICINE (2010)
The causes of cancer revisited: Mitochondrial malignancy and ROS-induced oncogenic transformation - Why mitochondria are targets for cancer therapy
Stephen J. Ralph et al.
MOLECULAR ASPECTS OF MEDICINE (2010)
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
Frank Weinberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Redox characterization of human cyclophilin D: Identification of a new mammalian mitochondrial redox sensor?
Dominique Linard et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2009)
No Selenium Required: Reactions Catalyzed by Mammalian Thioredoxin Reductase That Are Independent of a Selenocysteine Residue
Adam P. Lothrop et al.
BIOCHEMISTRY (2009)
New, Long-term Insights from the Adenoma Prevention with Celecoxib Trial on a Promising but Troubled Class of Drugs
Raymond N. DuBois
CANCER PREVENTION RESEARCH (2009)
Five-Year Efficacy and Safety Analysis of the Adenoma Prevention with Celecoxib Trial
Monica M. Bertagnolli et al.
CANCER PREVENTION RESEARCH (2009)
Role of cardiolipin peroxidation and Ca2+ in mitochondrial dysfunction and disease
Giuseppe Paradies et al.
CELL CALCIUM (2009)
Inhibition of Schistosoma mansoni Thioredoxin-glutathione Reductase by Auranofin STRUCTURAL AND KINETIC ASPECTS
Francesco Angelucci et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells
Cesar A. Corzo et al.
JOURNAL OF IMMUNOLOGY (2009)
HIF-1 alpha Modulates Energy Metabolism in Cancer Cells by Inducing Over-Expression of Specific Glycolytic Isoforms
Alvaro Marin-Hernandez et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2009)
Mitocans, a class of emerging anti-cancer drugs
Stephen J. Ralph et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2009)
Double blind randomized phase II study with radiation+5-fluorouracil ± celecoxib for resectable rectal cancer
Annelies Debucquoy et al.
RADIOTHERAPY AND ONCOLOGY (2009)
Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype
Binod Kumar et al.
CANCER RESEARCH (2008)
Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials - The cross trial safety analysis
Scott D. Solomon et al.
CIRCULATION (2008)
Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours
S. Toffoli et al.
FEBS JOURNAL (2008)
Tumor cell metabolism imaging
Christian Plathow et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Cell Death by SecTRAPs: Thioredoxin Reductase as a Prooxidant Killer of Cells
Karin Anestal et al.
PLOS ONE (2008)
Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration -: Implications for the mechanism of HIF-1α stabilization under moderate hypoxia
Stephen W. Tuttle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Auranofin blocks interleukin-6 signalling by inhibiting phosphorylation of JAK1 and STAT3
Nam-Hoon Kim et al.
IMMUNOLOGY (2007)
Lactate sensitive transcription factor network in L6 cells:: activation of MCT1 and mitochondrial biogenesis
Takeshi Hashimoto et al.
FASEB JOURNAL (2007)
Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells
Christine Marzano et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Mitocans: Mitochondrial targeted anti-cancer drugs as improved therapies and related patent documents
Stephen J. Ralph et al.
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY (2006)
Celecoxib for the prevention of colorectal adenomatous polyps
Nadir Arber et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Retrospective study of capecitabine and celecoxib in metastatic colorectal cancer - Potential benefits and COX-2 as the common mediator in pain, toxicities and survival?
Edward H. Lin et al.
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS (2006)
Mitochondrial ROS-induced ROS release: An update and review
Dmitry B. Zorov et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2006)
Thioredoxin reductase is irreversibly modified by curcumin - A novel molecular mechanism for its anticancer activity
JG Fang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
S-glutathionylation in human platelets by a thiol-disulfide exchange-independent mechanism
I Dalle-Donne et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
SD Solomon et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity
EO Hileman et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2004)
Ca2+-induced reactive oxygen species production promotes cytochrome c release from rat liver mitochondria via mitochondrial permeability transition (MPT)-dependent and MPT-independent mechanisms -: Role of cardiolipin
G Petrosillo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Auranofin induces apoptosis and when combined with retinoic acid enhances differentiation of acute promyelocytic leukaemia cells in vitro
IS Kim et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function
M Conrad et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Hypoxic reduction in cellular glutathione levels requires mitochondrial reactive oxygen species
KD Mansfield et al.
JOURNAL OF APPLIED PHYSIOLOGY (2004)
Oxidative stress in malignant melanoma and non-melanoma skin cancer
CS Sander et al.
BRITISH JOURNAL OF DERMATOLOGY (2003)
Induction of mitochondrial permeability transition by auranofin, a gold(I)-phosphine derivative
MP Rigobello et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Retention mechanism of hypoxia selective nuclear imaging/radiotherapeutic agent Cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM) in tumor cells
A Obata et al.
ANNALS OF NUCLEAR MEDICINE (2001)
Analysis of the inhibition of mammalian thioredoxin, thioredoxin reductase, and glutaredoxin by cis-diamminedichloroplatinum (II) and its major metabolite, the glutathione-platinum complex
ESJ Arnér et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress
M Benhar et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
G Steinbach et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients
O Portakal et al.
CLINICAL BIOCHEMISTRY (2000)
分享论文
