期刊
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
卷 98, 期 -, 页码 834-842出版社
ELSEVIER
DOI: 10.1016/j.msec.2019.01.002
关键词
Fluorescent carbon dots; Fe3+ ion; Cancer cells; Tomato; Fluoresce spectroscopy and microscopy
资金
- Brain Pool Program through the Korean Federation of Science and Technology Societies (KOFST)
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science and ICT [172S-4-3-1923, NRF-2017R1A2B4009581, NRF-2018R1A4A1022647]
- National Research Foundation of Korea [22A20130012543, 2018R1A4A1022647, 172S-4-3-1923] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Herein, we report a facile one-step synthetic strategy for fabrication of three (blue, green and yellow) fluorescent color carbon dots (CDs) from tomato (Solanum lycopersicum). The as-synthesized CDs showed emission peaks at 450, 520 and 560 nm for blue, green and yellow color CDs when excited at 370, 420 and 460 nm, respectively. Using tomato as a carbon source, the fabricated three fluorescent color CDs showed good water dispersity and high quantum yield. The analytical performances of three fluorescent color CDs are evaluated by detecting Fe3+ ion in biofluids and iron tablets. Upon the addition of Fe3+ ion under optimal conditions, the fluorescence intensity of three fluorescent color CDs was quenched linearly over the range of 0.1 to 2.0 mu M. This method opens a new analytical strategy to quantify Fe3+ ion in iron tablets and biofluids with high sensitivity. Further, the uptake of three fluorescent color CDs into HeLa cells was confirmed by confocal laser scanning microscopy. Intracellular experiments demonstrated that the three fluorescent color CDs were effectively internalized the cells and show excellent biocompatibility and low toxicity, suggesting that the CDs can be used as good candidates for biomedical applications.
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