相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Effects of Daprodustat, a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor on Anemia Management in Japanese Hemodialysis Subjects
Tadao Akizawa et al.
AMERICAN JOURNAL OF NEPHROLOGY (2017)
Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses
Pranvera Sadiku et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance
Ruth C. R. Meex et al.
NATURE REVIEWS ENDOCRINOLOGY (2017)
Phase 2 studies of oral hypoxia-inducible factor prolyl hydroxylase inhibitor FG-4592 for treatment of anemia in China
Nan Chen et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2017)
Discovery of JTZ-951: A HIF Prolyl Hydroxylase Inhibitor for the Treatment of Renal Anemia
Yosuke Ogoshi et al.
ACS MEDICINAL CHEMISTRY LETTERS (2017)
Roxadustat (FG-4592) Versus Epoetin Alfa for Anemia in Patients Receiving Maintenance Hemodialysis: A Phase 2, Randomized, 6-to 19-Week, Open-Label, Active-Comparator, Dose-Ranging, Safety and Exploratory Efficacy Study
Robert Provenzano et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2016)
Hypoxia-Inducible Factor Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis
Lea Rahtu-Korpela et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2016)
Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat (FG-4592) for the Treatment of Anemia in Patients with CKD
Robert Provenzano et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)
Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia
Elke Marsch et al.
EUROPEAN HEART JOURNAL (2016)
Adiponectin as a target for the treatment of nonalcoholic steatohepatitis with thiazolidinediones: A systematic review
Stergios A. Polyzos et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2016)
HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity
Hiroaki Semba et al.
NATURE COMMUNICATIONS (2016)
Kruppel-like factor 6 regulates mitochondrial function in the kidney
Sandeep K. Mallipattu et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Increased Adipocyte O2 Consumption Triggers HIF-1α, Causing Inflammation and Insulin Resistance in Obesity
Yun Sok Lee et al.
CELL (2014)
HIF Prolyl 4-Hydroxylase-2 Inhibition Improves Glucose and Lipid Metabolism and Protects Against Obesity and Metabolic Dysfunction
Lea Rahtu-Korpela et al.
DIABETES (2014)
Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis
Miyako Tanaka et al.
NATURE COMMUNICATIONS (2014)
CALL FOR PAPERS Renal Hypoxia Hypoxia as a key player in the AKI-to-CKD transition
Shinji Tanaka et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2014)
Regulation of erythropoiesis by hypoxia-inducible factors
Volker H. Haase
BLOOD REVIEWS (2013)
Prolyl Hydroxylase Domain Protein 2 Plays a Critical Role in Diet-Induced Obesity and Glucose Intolerance
Hirohide Matsuura et al.
CIRCULATION (2013)
A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition
Kevin Wei et al.
NATURE MEDICINE (2013)
Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes
Cullen M. Taniguchi et al.
NATURE MEDICINE (2013)
Mechanisms of Chronic State of Inflammation as Mediators That Link Obese Adipose Tissue and Metabolic Syndrome
Eduardo Fuentes et al.
MEDIATORS OF INFLAMMATION (2013)
Myeloid Cell-Derived Hypoxia-Inducible Factor Attenuates Inflammation in Unilateral Ureteral Obstruction-Induced Kidney Injury
Hanako Kobayashi et al.
JOURNAL OF IMMUNOLOGY (2012)
The Differential Role of Hif1 β/Arnt and the Hypoxic Response in Adipose Function, Fibrosis, and Inflammation
Kevin Y. Lee et al.
CELL METABOLISM (2011)
Is there an obesity-metabolic syndrome related glomerulopathy?
Eberhard Ritz et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2011)
Blockade of IL-6 signaling exacerbates liver injury and suppresses antiapoptotic gene expression in methionine choline-deficient diet-Fed db/db mice
Kanji Yamaguchi et al.
LABORATORY INVESTIGATION (2011)
Clinicopathological Characteristics of Obesity-associated Focal Segmental Glomerulosclerosis
Sihem Darouich et al.
ULTRASTRUCTURAL PATHOLOGY (2011)
Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors
John T. Heiker et al.
BIOLOGICAL CHEMISTRY (2010)
The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease
Stergios A. Polyzos et al.
DIABETES OBESITY & METABOLISM (2010)
Hypoxia-inducible factor-1α regulates β cell function in mouse and human islets
Kim Cheng et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Activation of a HIF1α-PPARγ Axis Underlies the Integration of Glycolytic and Lipid Anabolic Pathways in Pathologic Cardiac Hypertrophy
Jaya Krishnan et al.
CELL METABOLISM (2009)
Systemic Fate of the Adipocyte-Derived Factor Adiponectin
Nils Halberg et al.
DIABETES (2009)
Xenon Preconditioning Protects against Renal Ischemic-Reperfusion Injury via HIF-1α Activation
Daqing Ma et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Hypoxia-Inducible Factor 2 Regulates Hepatic Lipid Metabolism
Erinn B. Rankin et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Adiponectin in Patients with Chronic Kidney Disease
Marcin Adamczak et al.
SEMINARS IN DIALYSIS (2009)
Diet-induced obesity is associated with hyperleptinemia, hyperinsulinemia, hepatic steatosis, and glomerulopathy in C57Bl/6J mice
Undi Hoffler et al.
ENDOCRINE (2009)
pVHL is a regulator of glucose metabolism and insulin secretion in pancreatic β cells
Jens Zehetner et al.
GENES & DEVELOPMENT (2008)
Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
I. Murano et al.
JOURNAL OF LIPID RESEARCH (2008)
Podocyte injury in focal segmental glomerulosclerosis: Lessons from animal models (a play in five acts)
V. D. D'Agati
KIDNEY INTERNATIONAL (2008)
Adipocyte death, adipose tissue remodeling, and obesity complications
Katherine J. Strissel et al.
DIABETES (2007)
Adipogenesis in obesity requires close interplay between differentiating adipocytes, strontal cells, and blood vessels
Satoshi Nishimura et al.
DIABETES (2007)
High-fat diets: Modeling the metabolic disorders of human obesity in rodents
Roland Buettner et al.
OBESITY (2007)
Inflammation and metabolic disorders
Goekhan S. Hotamisligil
NATURE (2006)
Podocyte lesions in patients with obesity-related glomerulopathy
Hui-Mei Chen et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2006)
Epidemiology of obesity and chronic kidney disease
Will R. Ross et al.
ADVANCES IN CHRONIC KIDNEY DISEASE (2006)
Is obesity an inflammatory illness?: Role of low-grade inflammation and macrophage infiltration in human white adipose tissue
R. Cancello et al.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2006)
Interleukin-6 is a key mediator of the hepatoprotective and pro-proliferative effects of ischaemic preconditioning in mice
Narci Teoh et al.
JOURNAL OF HEPATOLOGY (2006)
Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure
Wanja M. Bernhardt et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
Hajime Kanda et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Obesity-related cardiovascular disease: implications of obstructive sleep apnea
R Wolk et al.
DIABETES OBESITY & METABOLISM (2006)
Obesity and cardiovascular disease - Pathophysiology, evaluation, and effect of weight loss
P Poirier et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Hepatic steatosis in the absence of tumor necrosis factor in mice
S Schnyder-Candrian et al.
CYTOKINE (2005)
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
S Cinti et al.
JOURNAL OF LIPID RESEARCH (2005)
Relation of microalbuminuria to adiponectin and augmented C-reactive protein levels in men with essential hypertension
C Tsioufis et al.
AMERICAN JOURNAL OF CARDIOLOGY (2005)
Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway
T Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
High adiponectin in chronic liver disease and cholestasis suggests biliary route of adiponectin excretion in vivo
F Tacke et al.
JOURNAL OF HEPATOLOGY (2005)
Decreased plasma adiponectin concentrations are closely associated with nonalcoholic hepatic steatosis in obese individuals
G Targher et al.
CLINICAL ENDOCRINOLOGY (2004)
Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats
M Matsumoto et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Nonalcoholic fatty liver disease
JM Clark et al.
GASTROENTEROLOGY (2002)
Obesity-related glomerulopathy: An emerging epidemic
N Kambham et al.
KIDNEY INTERNATIONAL (2001)
TNF-alpha is not the cause of fatty liver disease in obese diabetic mice
RA Memon et al.
NATURE MEDICINE (2001)
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
K Hotta et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)
Development of high fat diet-induced obesity and leptin resistance in C57BI/6J mice
S Lin et al.
INTERNATIONAL JOURNAL OF OBESITY (2000)