期刊
JOURNAL OF SEPARATION SCIENCE
卷 42, 期 14, 页码 2303-2340出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.201900159
关键词
chirality; enantioslective separation; HPLC; monoliths
资金
- Egyptian Cultural Affairs and the University of Canberra Funding Source: Medline
In this review, three main classes of chiral monolithic stationary phases, namely silica-, organic polymer-, and hybrid-based monolithic stationary phases, are covered. Their preparations, applications, and advantages compared with the conventional-packed and open-tubular capillary columns are discussed. A detailed description of the different types and techniques used for the introduction of chiral selectors into the monolithic matrices such as immobilization, functionalization, coating, encapsulation, and bonding. Special emphasis is given to the recent developments of chiral selectors in HPLC monolithic stationary phases during the past 18 years.
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