Cu-catalyzed arylation of 1-acyl-1H-1,2,3-Benzotriazoles via C-N activation

An efficient copper-catalyzed arylation reaction of 1-acyl-1H-1,2,3-benzotriazoles with diaryliodonium salts via C-N activation is explored. The reaction is conducted regioselectively to form 1-aryl-1H-1,2,3-benzotriazoles in MeCN at 80 degrees C in the presence of cesium carbonate. 29 examples are given with the product yield of up to 84%. The probable reaction mechanism is proposed. (c) 2019 Elsevier B.V. All rights reserved.