期刊
JOURNAL OF NUCLEAR MEDICINE
卷 60, 期 8, 页码 1044-1052出版社
SOC NUCLEAR MEDICINE INC
DOI: 10.2967/jnumed.118.217901
关键词
PET; neuroimaging; high spatial resolution; multimodal imaging
资金
- NIH BRAIN Initiative [1R01 EB026995]
Whole-body PET scanners are not optimized for imaging small structures in the human brain. Several PET devices specifically designed for this task have been proposed either for stand-alone operation or as MR-compatible inserts. The main distinctive features of some of the most recent concepts and their performance characteristics, with a focus on spatial resolution and sensitivity, are reviewed. The trade-offs between the various performance characteristics, desired capabilities, and cost that need to be considered when designing a dedicated brain scanner are presented. Finally, the aspirational goals for future-generation scanners, some of the factors that have contributed to the current status, and how recent advances may affect future developments in dedicated brain PET instrumentation are briefly discussed.
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