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Emerging therapies for non-small cell lung cancer

期刊

JOURNAL OF HEMATOLOGY & ONCOLOGY
卷 12, 期 -, 页码 -

出版社

BMC
DOI: 10.1186/s13045-019-0731-8

关键词

Tyrosine kinase inhibitors; Checkpoint inhibitors; CAR-T; Bispecific antibodies; Lung cancer

资金

  1. National Natural Science Foundation [81673031, 81872510]

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Recent advances in the field of novel anticancer agents prolong patients' survival and show a promising future. Tyrosine kinase inhibitors and immunotherapy for lung cancer are the two major areas undergoing rapid development. Although increasing novel anticancer agents were innovated, how to translate and optimize these novel agents into clinical practice remains to be explored. Besides, toxicities and availability of these drugs in specific regions should also be considered during clinical determination. Herein, we summarize emerging agents including tyrosine kinase inhibitors, checkpoint inhibitors, and other potential immunotherapy such as chimeric antigen receptor T cell for non-small cell lung cancer attempting to provide insights and perspectives of the future in anticancer treatment.

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