Antimicrobial, Cytotoxicity and Photocatalytic Degradation of Norfloxacin Using Kleinia grandiflora Mediated Silver Nanoparticles

Synthesis of nanomaterials through green and eco-friendly approaches which are free from toxic chemicals is an emerging interest in the field of nanoscience and nanotechnology. Plant-mediated synthesis of silver nanoparticles (AgNPs) gained importance because of its non-toxic, eco-friendly and potential for biomedical applications. The present study explored the synthesis of AgNPs using Kleinia grandiflora leaf extract (KGLE) as a reducing and stabilizing agent. The synthesized AgNPs were characterized via UV-Vis spectroscopy (UV-Vis), Fourier transform-infrared spectroscopy, X-ray diffraction, scanning electron microscopy, transmission electron microscopy and energy dispersive X-ray spectroscopy. The biosynthesized AgNPs were found to be spherical in shape and particle size in the range of 20-50 nm. Besides, the synthesized AgNPs showed significant antimicrobial efficacy against Pseudomonas aeruginosa and Aspergillus niger as well as considerable cytotoxicity towards Dalton's lymphoma ascites cells with 100% inhibition at the concentration of 200 mu g/mL of Ag-NPs. Furthermore, the photocatalytic degradation of norfloxacin under visible light irradiation explored the better reducing ability after 80 min of exposure time It is envisioned that KGLE mediated synthesized AgNPs may have a better antimicrobial, cytotoxic and photocatalytic agent in future.