期刊
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
卷 22, 期 7, 页码 647-654出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2019.1612380
关键词
Phoma sp; epoxydon derivative; benzolactone; antioxidant activity
资金
- National Natural Science Foundation of China [U1604176]
- Science and Technology Planning Project of He'nan Province [182102310651]
- Programs Foundation of Zhengzhou University of Light Industry [13501050056]
One new epoxydon ester (1) and a new benzolactone derivative (2), along with four known compounds (3-6), were isolated from the insect-associated fungus Phoma sp. Their structures were confirmed by extensive MS and NMR spectroscopic analysis and their absolute configurations were determined by a combination of modified Mosher method and Mo-2(OCOCH3)(4)-induced electronic circular dichroism (ECD) experiments. Compounds 1 and 5 were revealed to have potent antioxidant activities, which were approximate to the potency of the positive control trolox. In addition, 1 also exhibited moderate cytotoxic effect against human MGC-803 tumor cell line. [GRAPHICS] .
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