期刊
JOURNAL OF ANTIBIOTICS
卷 72, 期 7, 页码 513-517出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41429-019-0178-8
关键词
-
资金
- Foundation for the National Natural Science Foundation of China [21662012]
- Program for Innovative Research Team in University [IRT-16R19]
Three new polyketides, (2S)-2,3-dihydro-5,6-dihydroxy-2-methyl-4H-1-benzopyran-4-one (1), (2'R)-2-(2'-hydroxypropyl)-4-methoxyl-1,3-benzenediol (2), and 4-ethyl-3-hydroxy-6-propenyl-2H-pyran-2-one (3) were isolated from the culture broth of Colletotrichum gloeosporioides, an endophytic fungus derived from the mangrove Ceriops tagal. The structures of 1-3 were elucidated on the basis of NMR spectra and HR-ESI-MS data. Their absolute configurations were determined by comparing with the experimental and calculated ECD spectrum. Compounds 1 and 3 showed potent antibacterial activities against some of the tested microbes.
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