期刊
JOURNAL OF ANIMAL SCIENCE
卷 97, 期 7, 页码 3142-3152出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/jas/skz157
关键词
livestock; metabolism; nutrition
资金
- USDA National Institute of Food and Agriculture AFRI [2013-01919, 2016-67016-24863]
- University of Connecticut Office of the Vice President for Research
- Storrs Agricultural Experiment Stations
- NIFA [2016-67016-24863, 810838] Funding Source: Federal RePORTER
Poor maternal nutrition, both restricted-feeding and overfeeding, during gestation can negatively affect offspring growth, body composition, and metabolism. The effects are observed as early as the prenatal period and often persist through postnatal growth and adulthood. There is evidence of multigenerational effects demonstrating the long-term negative impacts on livestock production. We and others have demonstrated that poor maternal nutrition impairs muscle growth, increases adipose tissue, and negatively affects liver function. In addition to altered growth, changes in key metabolic factors, increased glucose concentrations, insulin insensitivity, and hyperleptinemia are observed during the postnatal period. Furthermore, there is recent evidence of altered metabolism in specific tissues (e.g., muscle, adipose, and liver) and stem cells. The systemic and local changes in metabolism demonstrate the importance of determining the mechanism(s) by which maternal diet programs offspring growth and metabolism in an effort to develop novel management practices to improve the efficiency of growth and health in these offspring.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据