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MOLECULAR CANCER RESEARCH (2006)
Adenomatous polyposis coli (APC) differentially regulates β-catenin phosphorylation and ubiquitination in colon cancer cells
Jun Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Coupling endoplasmic reticulum stress to the cell-death program: a novel HSP90-independent role for the small chaperone protein p23
RV Rao et al.
CELL DEATH AND DIFFERENTIATION (2006)
Overexpression of glucose-regulated protein 78 in colon cancer
XM Xing et al.
CLINICA CHIMICA ACTA (2006)
Role of the unfolded protein response in cell death
R Kim et al.
APOPTOSIS (2006)
Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells
Gavin P. Collett et al.
CARCINOGENESIS (2006)
Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression
G Song et al.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2005)
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
EM Jung et al.
CARCINOGENESIS (2005)
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
MX Bi et al.
EMBO JOURNAL (2005)
Transforming growth factor β can mediate apoptosis via the expression of TRAIL in human hepatoma cells
K Herzer et al.
HEPATOLOGY (2005)
Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression
M Notarbartolo et al.
CANCER LETTERS (2005)
The inhibitory mechanism of curcumin and its derivative against β-catenin/Tef signaling
CH Park et al.
FEBS LETTERS (2005)
COX-2: A molecular target for colorectal cancer prevention
JR Brown et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Wnt signalling in stem cells and cancer
T Reya et al.
NATURE (2005)
Critical evaluation of current treatments in metastatic colorectal cancer
A Venook
ONCOLOGIST (2005)
Activation of PPARγ by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR
AP Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
Lipid peroxidation and antioxidant status in colorectal cancer
Elzbieta Skrzydlewska et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2005)
Mitochondrial H+ leak and ROS generation: An odd couple
PS Brookes
FREE RADICAL BIOLOGY AND MEDICINE (2005)
X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells
JM Cummins et al.
CANCER RESEARCH (2004)
ROS stress in cancer cells and therapeutic implications
H Pelicano et al.
DRUG RESISTANCE UPDATES (2004)
Modulation of AP-1 by natural chemopreventive compounds in human colon HT-29 cancer cell line
WS Jeong et al.
PHARMACEUTICAL RESEARCH (2004)
Modulatory properties of various natural chemopreventive agents on the activation of NF-κB signaling pathway
WS Jeong et al.
PHARMACEUTICAL RESEARCH (2004)
p53: 25 years after its discovery
LJ Hofseth et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration
G Garcea et al.
BRITISH JOURNAL OF CANCER (2004)
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
JE Chipuk et al.
SCIENCE (2004)
Cell death: Critical control points
NN Danial et al.
CELL (2004)
Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
E Hernando et al.
NATURE (2004)
Minireview: Cyclin D1: Normal and abnormal functions
MF Fu et al.
ENDOCRINOLOGY (2004)
A lipid peroxidation-derived inflammatory mediator - Identification of 4-hydroxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages
T Kumagai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
OJ Sansom et al.
GENES & DEVELOPMENT (2004)
Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells
GP Collett et al.
CARCINOGENESIS (2004)
Phase I clinical trial of oral curcumin: Biomarkers of systemic activity and compliance
RA Sharma et al.
CLINICAL CANCER RESEARCH (2004)
Increased expression of nuclear factor-kappa B/RelA is correlated with tumor angiogenesis in human colorectal cancer
HG Yu et al.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2004)
Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC
RA Green et al.
JOURNAL OF CELL BIOLOGY (2003)
Regulation of apoptosis by endoplasmic reticulum pathways
DG Breckenridge et al.
ONCOGENE (2003)
Cisplatin: mode of cytotoxic action and molecular basis of resistance
ZH Siddik
ONCOGENE (2003)
Ways of dying: multiple pathways to apoptosis
JM Adams
GENES & DEVELOPMENT (2003)
Survivin and molecular pathogenesis of colorectal cancer
PJ Kim et al.
LANCET (2003)
Molecular mechanisms of curcumin-induced cytotoxicity:: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt
JH Woo et al.
CARCINOGENESIS (2003)
NAD(P)H oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91phox in the regulated production of superoxide by phagocytes
M Geiszt et al.
JOURNAL OF IMMUNOLOGY (2003)
Genomic medicine - Hereditary colorectal cancer
HT Lynch et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Fas ligand expressed in colon cancer is not associated with increased apoptosis of tumor cells in vivo
A Houston et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
Role of reactive oxygen species and cardiolipin in the release of cytochrome c from mitochondria
G Petrosillo et al.
FASEB JOURNAL (2003)
Live and let die in the intestinal epithelium
E Sancho et al.
CURRENT OPINION IN CELL BIOLOGY (2003)
Changes in apoptosis during the development of colorectal cancer: a systematic review of the literature
JJ Koornstra et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2003)
Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation
A Mukhopadhyay et al.
ONCOGENE (2002)
β-Catenin-mediated transactivation and cell -: cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells
AS Jaiswal et al.
ONCOGENE (2002)
BID regulation by p53 contributes to chemosensitivity
JK Sax et al.
NATURE CELL BIOLOGY (2002)
An endoplasmic reticulum stress-specific caspase cascade in apoptosis -: Cytochrome c-independent activation of caspase-9 by caspase-12
N Morishima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Apoptotic threshold is lowered by p53 transactivation of caspase-6
TK MacLachan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Targeted inactivation of CTNNB1 reveals unexpected effects of β-catenin mutation
TA Chan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Activation of the p53 tumor suppressor protein
KH Vousden
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2002)
Bcl-2 family of proteins: Life-or-death switch in mitochondria
Y Tsujimoto
BIOSCIENCE REPORTS (2002)
P53 overexpression predicts poor chemosensitivity to high-dose 5-fluorouracil plus leucovorin chemotherapy for stage IV colorectal cancers after palliative bowel resection
JT Liang et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
H LeBlanc et al.
NATURE MEDICINE (2002)
Curcumin induces apoptosis in human melanoma cells through a Fas receptor/caspase-8 pathway independent of p53
JA Bush et al.
EXPERIMENTAL CELL RESEARCH (2001)
Involvement of the retinoblastoma (pRb)-E2F/DP pathway during anti proliferative effects of resveratrol in human epidermoid carcinoma (A431) cells
VM Adhami et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells
A Goel et al.
CANCER LETTERS (2001)
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells
PM Hwang et al.
NATURE MEDICINE (2001)
Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2
RA Gupta et al.
NATURE REVIEWS CANCER (2001)
Cyclo-oxygenase 2: a pharmacological target for the prevention of cancer
AJ Dannenberg et al.
LANCET ONCOLOGY (2001)
Target genes of peroxisome proliferator-activated receptor γ in colorectal cancer cells
RA Gupta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation of PTEN transcription by p53
V Stambolic et al.
MOLECULAR CELL (2001)
Cyclooxygenase-2: a novel target for cancer chemotherapy?
W Dempke et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2001)
DNA microarray analysis of genes involved in p53 mediated apoptosis: activation of Apaf-1
K Kannan et al.
ONCOGENE (2001)
The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis:: significance for the molecular mechanism of Bcl-2 action
P Pinton et al.
EMBO JOURNAL (2001)
Apaf-1 is a transcriptional target for E2F and p53
MC Moroni et al.
NATURE CELL BIOLOGY (2001)
Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
T Yoneda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Increased sensitivity to dextran sodium sulfate colitis in IRE1β-deficient mice
A Bertolotti et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Cyclooxygenase-two (COX-2) modulates proliferation in aggressive fibromatosis (desmoid tumor)
R Poon et al.
ONCOGENE (2001)
Nonsteroidal antiinflammatory drugs, cyclooxygenase-2, and colorectal cancer prevention
RN DuBois
CURRENT OPINION IN GASTROENTEROLOGY (2001)
CD95's deadly mission in the immune system
PH Krammer
NATURE (2000)
On the antioxidant mechanism of curcumin: Classical methods are needed to determine antioxidant mechanism and activity
LRC Barclay et al.
ORGANIC LETTERS (2000)
Cross-talk between two cysteine protease families: Activation of caspase-12 by calpain in apoptosis
T Nakagawa et al.
JOURNAL OF CELL BIOLOGY (2000)
Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis
K Nakamura et al.
JOURNAL OF CELL BIOLOGY (2000)
Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum
R Foyouzi-Youssefi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Cutting edge: The tumor counterattack hypothesis revisited: Colon cancer cells do not induce T cell apoptosis via the Fas (CD95, APO-1) pathway
N Favre-Felix et al.
JOURNAL OF IMMUNOLOGY (2000)
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
H Walczak et al.
EXPERIMENTAL CELL RESEARCH (2000)
Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis
NN Mahmoud et al.
CARCINOGENESIS (2000)
Protein expression of p53, p21 (WAF1/CIP1), bcl-2, Bax, cyclin D1 and pRb in human colon carcinomas
IK Bukholm et al.
VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY (2000)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
T Nakagawa et al.
NATURE (2000)
Lessons from genetically engineered animal models VII. Apoptosis in intestinal epithelium: lessons from transgenic and knockout mice
AJM Watson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2000)
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