Renal Tubular Acidosis Presenting as Nephrogenic Diabetes Insipidus

BackgroundNephrogenic diabetes insipidus (DI) can be primary or secondary to various causes.Case CharacteristicsOne child with Fanconi syndrome with proximal renal tubular acidosis (RTA) due to nephropathic cystinosis, and other with Distal RTA with hearing loss.ObservationBoth cases showed features of nephrogenic DI, which resolved after treating the primary pathology.MessageRenal Tubular acidosis may cause nephrogenic DI.