期刊
IMMUNOLOGY AND CELL BIOLOGY
卷 97, 期 7, 页码 636-646出版社
WILEY
DOI: 10.1111/imcb.12274
关键词
immunometabolism; memory T-cell metabolism; mitochondria
资金
- Max Planck Society
The development and persistence of memory T cells are integral to effective host defenses. Cell metabolism has a central role in the maintenance of these populations and engagement of specific metabolic pathways can influence T-cell fate. Nuances in memory T-cell metabolism are both context dependent, and exist, on a spectrum that complements and supports the activity of specific memory T-cell subsets. This review explores how metabolic pathways and substrate choice can influence the phenotype and function of memory T cells.
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