期刊
ANNALS OF NEUROLOGY
卷 79, 期 6, 页码 1026-1030出版社
WILEY
DOI: 10.1002/ana.24646
关键词
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资金
- Oesterreichische Nationalbank (Austrian Central Bank, Anniversary Fund) [14174]
- Austrian Science Fund (FWF: Der Wissenschaftsfonds) [KLI82-B00]
- Austrian Science Fund (FWF) [KLI82] Funding Source: Austrian Science Fund (FWF)
- Austrian Science Fund (FWF) [KLI 82] Funding Source: researchfish
We assessed loss of dorsolateral nigral hyperintensity (DNH) on high-field susceptibility-weighted imaging (SWI), a novel magnetic resonance imaging marker for Parkinson's disease (PD), in 15 subjects with idiopathic rapid eye movement sleep behavior disorder (iRBD) and compared findings to 42 healthy controls (HCs) and 104 PD patients. We found loss of DNH in at least two thirds of iRBD subjects, which approaches the rate observed in PD and is in contrast to findings in HCs. We propose that absence of DNH on high-field SWI could identify prodromal degenerative parkinsonism in iRBD.
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