4.4 Article

Highlight article: Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Cell Biology

The Elusive P2X7 Macropore

Francesco Di Virgilio et al.

TRENDS IN CELL BIOLOGY (2018)

Article Neurosciences

Neuronal P2X7 Receptors Revisited: Do They Really Exist?

Peter Illes et al.

JOURNAL OF NEUROSCIENCE (2017)

Article Neurosciences

Neuronal P2X7 Receptor: Involvement in Neuronal Physiology and Pathology

M. Teresa Miras-Portugal et al.

JOURNAL OF NEUROSCIENCE (2017)

Editorial Material Cell Biology

P2X7 receptor antagonism in amyotrophic lateral sclerosis

Ronald Sluyter et al.

NEURAL REGENERATION RESEARCH (2017)

Review Cell Biology

Current view and perspectives in amyotrophic lateral sclerosis

Stephane Mathis et al.

NEURAL REGENERATION RESEARCH (2017)

Review Neurosciences

Purinergic contribution to amyotrophic lateral sclerosis

Cinzia Volonte et al.

NEUROPHARMACOLOGY (2016)

Article Pharmacology & Pharmacy

HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus

Keisuke Migita et al.

MOLECULAR PHARMACOLOGY (2016)

Review Chemistry, Medicinal

Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity

Annerleim Walton-Diaz et al.

FUTURE MEDICINAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

P2X7 receptor-induced death of motor neurons by a peroxynitrite/FAS-dependent pathway

Mandi Gandelman et al.

JOURNAL OF NEUROCHEMISTRY (2013)

Article Multidisciplinary Sciences

Nitration of Hsp90 induces cell death

Maria Clara Franco et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Biochemistry & Molecular Biology

Post-translational modifications of Hsp90 and their contributions to chaperone regulation

Mehdi Mollapour et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)

Article Pharmacology & Pharmacy

Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X7 receptor antagonist: a prospective genotyping approach

Simon M. McHugh et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2012)

Article Neurosciences

P2X7 Receptors: Channels, Pores and More

C. Volonte et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2012)

Article Biochemistry & Molecular Biology

Geldanamycin and its derivatives as Hsp90 inhibitors

Magdalena Gorska et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2012)

Article Multidisciplinary Sciences

Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis

Pablo Diaz-Amarilla et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Biochemistry & Molecular Biology

PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons

Ke Ning et al.

HUMAN MOLECULAR GENETICS (2010)

Article Biochemistry & Molecular Biology

Cu, Zn-Superoxide Dismutase Increases Toxicity of Mutant and Zinc-deficient Superoxide Dismutase by Enhancing Protein Stability

Mary Anne Garner et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Biochemistry & Molecular Biology

The Heat Shock Response: Life on the Verge of Death

Klaus Richter et al.

MOLECULAR CELL (2010)

Article Biochemistry & Molecular Biology

Swe1Wee1-Dependent Tyrosine Phosphorylation of Hsp90 Regulates Distinct Facets of Chaperone Function

Mehdi Mollapour et al.

MOLECULAR CELL (2010)

Article Cell Biology

Extracellular ATP dissociates nonmuscle myosin from P2X7 complex: this dissociation regulates P2X7 pore formation

Ben J. Gu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2009)

Review Oncology

Targeting HSP90 for cancer therapy

D. Mahalingam et al.

BRITISH JOURNAL OF CANCER (2009)

Article Biochemistry & Molecular Biology

PI3K/PTEN signaling in tumorigenesis and angiogenesis

Bing-Hua Jiang et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2008)

Article Neurosciences

Cellular localization of P2X7 receptor mRNA in the rat brain

Yong Yu et al.

BRAIN RESEARCH (2008)

Review Chemistry, Medicinal

Medicinal chemistry of Hsp90 inhibitors

Martin J. Drysdale et al.

CURRENT TOPICS IN MEDICINAL CHEMISTRY (2008)

Editorial Material Biochemistry & Molecular Biology

The Hsp90 chaperone machinery regulates signaling by modulating ligand binding clefts

William B. Pratt et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Review Biochemistry & Molecular Biology

Prevention of peroxynitrite-induced apoptosis of motor neurons and PC12 cells by tyrosine-containing peptides

Yaozu Ye et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Multidisciplinary Sciences

Onset and progression in inherited ALS determined by motor neurons and microglia

Severine Boillee et al.

SCIENCE (2006)

Article Neurosciences

Extracellular heat shock protein 70: A critical component for motoneuron survival

MB Robinson et al.

JOURNAL OF NEUROSCIENCE (2005)

Review Oncology

HSP90 and the chaperoning of cancer

L Whitesell et al.

NATURE REVIEWS CANCER (2005)

Article Biochemistry & Molecular Biology

Tyrosine phosphorylation of HSP90 within the P2X7 receptor complex negatively regulates P2X7 receptors

E Adinolfi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Review Medicine, Research & Experimental

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

WB Pratt et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2003)

Review Biochemistry & Molecular Biology

Heat-shock protein 90, a chaperone for folding and regulation

D Picard

CELLULAR AND MOLECULAR LIFE SCIENCES (2002)

Review Physiology

Molecular physiology of P2X receptors

RA North

PHYSIOLOGICAL REVIEWS (2002)

Article Neurosciences

Raf and akt mediate distinct aspects of sensory axon growth

A Markus et al.

NEURON (2002)

Article Biochemistry & Molecular Biology

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1

N Fujita et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Proteomic and functional evidence for a P2X7 receptor signalling complex

M Kim et al.

EMBO JOURNAL (2001)

Review Cell Biology

Hsp90: Chaperoning signal transduction

K Richter et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2001)

Article Biochemistry & Molecular Biology

Differential assembly of rat purinergic P2X7 receptor in immune cells of the brain and periphery

M Kim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Review Biochemistry & Molecular Biology

Structure and in vivo function of Hsp90

LH Pearl et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2000)

Article Biochemistry & Molecular Biology

Liposome-delivered superoxide dismutase prevents nitric oxide-dependent motor neuron death induced by trophic factor withdrawal

AG Estévez et al.

FREE RADICAL BIOLOGY AND MEDICINE (2000)