期刊
CURRENT OPINION IN PULMONARY MEDICINE
卷 25, 期 3, 页码 225-232出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MCP.0000000000000571
关键词
intravenous immunoglobulin; necrotizing pneumonia; Panton-Valentine leukocidin; pulmonary gangrene; Staphylococcus aureus
Purpose of review Necrotizing pneumonia is a severe form of community-acquired pneumonia characterized by rapid progression of consolidation to necrosis and cavitation which may lead to pulmonary gangrene. Morbidity and mortality are high and chronic sequelae are frequent. The lack of guidance supports the review of the latest recommendations in the management of these pneumonias. Recent findings Antibiotic therapy alone may not be enough to alter the course of the infection, and regimens, adjunctive therapies like intravenous immunoglobulins, surgery may be required to alter the course of the disease especially with pulmonary gangrene. Summary The causative agents, clinical features and management of necrotizing pneumonias are discussed.
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