期刊
CURRENT OPINION IN PLANT BIOLOGY
卷 48, 期 -, 页码 9-17出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2019.01.001
关键词
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资金
- European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant [H2020-MSCA-ITN-2015-675752]
Genome annotations offer ample opportunities to study gene functions, biochemical and regulatory pathways, or quantitative trait loci in plants. Determining the quality and completeness of a genome annotation, and maintaining the balance between them, are major challenges, even for genomes of well-studied model organisms. In this review, we present a historical overview of the complexity in different plant genomes and discuss the hurdles and possible solutions in obtaining a complete and high-quality genome annotation. We illustrate there is no clear-cut answer to solve these challenges for different gene types, but provide tips on guiding the iterative process of generating a superior genome annotation, which is a moving target as our knowledge about plant genomics increases and additional data sources become available.
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