期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 25, 期 40, 页码 9366-9384出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201901026
关键词
annulation; C-H activation; green solvents; heterocycles; transition metals
资金
- Ministry of Science and Technology of the Republic of China [MOST 107-2113-M-007-004]
Catalytic C-H functionalization has emerged as an efficient alternative to traditional coupling reactions. However, some of these reactions depend on environmentally harmful solvents, weakening the overall green nature of these methods. As organic processes consume large amount of solvents, the use of less harmful solvents enhance the sustainability of these reactions. Herein, we present an overview of transition metal-catalyzed C-H functionalization reactions for the synthesis of heterocycles in sustainable solvents based on CHEM21 solvent selection guide.
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