4.6 Article

XANES/EPR Evidence of the Oxidation of Nickel(II) Quinolinylpropioamide and Its Application in Csp3-H Functionalization

期刊

CHEMISTRY-A EUROPEAN JOURNAL
卷 25, 期 19, 页码 4931-4934

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201900009

关键词

Csp(3)-H functionalization; EPR spectroscopy; Ni catalyst; Ni-III species; X-ray absorption spectroscopy

资金

  1. National Natural Science Foundation of China [21701127, 21762023, 21520102003]
  2. Hubei Province Natural Science Foundation of China [2017CFB152]
  3. Natural Science Foundation of Jiangxi Province of China [2018BAB203006]
  4. Fundamental Research Funds for the Central Universities [213413000050]
  5. Scientific Research Foundation of Wuhan University [413100043, 413100021]

向作者/读者索取更多资源

An in situ generated oxidation species of nickel quinolinylpropioamide intermediate was produced. Characterization by X-ray absorption near edge structure (XANES) and EPR provides complementary insights into this oxidized nickel species. With aliphatic amides and isocyanides as substrates, a nickel-catalyzed facile synthesis of structurally diverse five-membered lactams could be achieved.

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