Planar-Chiral [2.2]Paracyclophane-Based Pyridonates as Ligands for Tantalum-Catalyzed Hydroaminoalkylation

By using planar chiral [2.2]paracyclophane-containing N,O-chelating ligands for tantalum-catalyzed hydroaminoalkylation, one of the most versatile catalytic systems for this reaction to date was obtained. Convenient C-sp3-C-sp3 bond formation of amines with terminal and internal alkenes was enabled by the same insitu synthesized catalytic system of [2.2]paracyclophane-based pyridonates and Ta(CH2TMS)(3)Cl-2 that shows also very promising results for N-containing heterocycles.