相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。GDNF revisited: A novel mammalian cell-derived variant form of GDNF increases dopamine turnover and improves brain biodistribution
Richard Grondin et al.
NEUROPHARMACOLOGY (2019)
Trophic factors for Parkinson's disease: Where are we and where do we go from here?
Gesine Paul et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2019)
Randomized trial of intermittent intraputamenal glial cell line-derived neurotrophic factor in Parkinson's disease
Alan Whone et al.
BRAIN (2019)
MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP
Yahui Yan et al.
NATURE COMMUNICATIONS (2019)
Pericytes secrete pro-regenerative molecules in response to platelet-derived growth factor-BB
Abderahim Gaceb et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2018)
Cerebral Dopamine Neurotrophic Factor (CDNF) Has Neuroprotective Effects against Cerebral Ischemia That May Occur through the Endoplasmic Reticulum Stress Pathway
Geng-Lin Zhang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling
Jenny Sandmark et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Nigrostriatal dopamine transporter availability in early Parkinson's disease
Patrik Fazio et al.
MOVEMENT DISORDERS (2018)
Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease
Gabriela Mercado et al.
NEUROBIOLOGY OF DISEASE (2018)
Toxic properties of microsome-associated alpha-synuclein species in mouse primary neurons
Emanuela Colla et al.
NEUROBIOLOGY OF DISEASE (2018)
Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease
Antti Huotarinen et al.
NEUROSCIENCE (2018)
ER Proteostasis Control of Neuronal Physiology and Synaptic Function
Gabriela Martinez et al.
TRENDS IN NEUROSCIENCES (2018)
Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection
Meirong Bai et al.
NATURE COMMUNICATIONS (2018)
CDNF induces the adaptive unfolded protein response and attenuates endoplasmic reticulum stress-induced cell death
Duxan Arancibia et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2018)
Gene therapy for neurological disorders: progress and prospects (vol 17, pg 641, 2018)
Benjamin E. Deverman et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
C. elegans MANF Homolog Is Necessary for the Protection of Dopaminergic Neurons and ER Unfolded Protein Response
Cory Richman et al.
FRONTIERS IN NEUROSCIENCE (2018)
Evaluation of the Parkinson's KinetiGraph in monitoring and managing Parkinson's disease
Parisa Farzanehfar et al.
EXPERT REVIEW OF MEDICAL DEVICES (2017)
Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons
Sabrina M. Heman-Ackah et al.
HUMAN MOLECULAR GENETICS (2017)
Endoplasmic reticulum stress and inflammation in the central nervous system
Neil T. Sprenkle et al.
MOLECULAR NEURODEGENERATION (2017)
Alpha-Synuclein mRNA Is Not Increased in Sporadic PD and Alpha-Synuclein Accumulation Does Not Block GDNF Signaling in Parkinson's Disease and Disease Models
Xiaomin Su et al.
MOLECULAR THERAPY (2017)
OBESITY Receptors identified for a weight regulator
Mart Saarma et al.
NATURE (2017)
Non - homeostatic body weight regulation through a brainstem-restricted receptor for GDF15
Jer-Yuan Hsu et al.
NATURE (2017)
Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next?
Raymond T. Bartus et al.
NEUROBIOLOGY OF DISEASE (2017)
Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 1: Where have we been and what have we learned?
Raymond T. Bartus et al.
NEUROBIOLOGY OF DISEASE (2017)
Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential
Maria Lindahl et al.
NEUROBIOLOGY OF DISEASE (2017)
A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat
Yulia A. Sidorova et al.
FRONTIERS IN PHARMACOLOGY (2017)
Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra
Kert Matlik et al.
ENEURO (2017)
Endoplasmic Reticulum Stress Interacts With Inflammation in Human Diseases
Stewart Siyan Cao et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2016)
The unfolded protein response: mechanisms and therapy of neurodegeneration
Heather L. Smith et al.
BRAIN (2016)
The UPR and synaptic dysfunction in neurodegeneration
Oliver J. Freeman et al.
BRAIN RESEARCH (2016)
Chronic, intermittent convection-enhanced delivery devices
Owen Lewis et al.
JOURNAL OF NEUROSCIENCE METHODS (2016)
Protein misfolding in the endoplasmic reticulum as a conduit to human disease
Miao Wang et al.
NATURE (2016)
Developing therapeutically more efficient Neurturin variants for treatment of Parkinson's disease
Pia Runeberg-Roos et al.
NEUROBIOLOGY OF DISEASE (2016)
Transplantation of Cerebral Dopamine Neurotrophic Factor Transducted BMSCs in Contusion Spinal Cord Injury of Rats: Promotion of Nerve Regeneration by Alleviating Neuroinflammation
Hua Zhao et al.
MOLECULAR NEUROBIOLOGY (2016)
Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson's Disease
Enrique Garea-Rodriguez et al.
PLOS ONE (2016)
Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes
Emilia Galli et al.
SCIENTIFIC REPORTS (2016)
Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial
C. Warren Olanow et al.
ANNALS OF NEUROLOGY (2015)
Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice
Susanna Kemppainen et al.
BEHAVIOURAL BRAIN RESEARCH (2015)
Key subdomains in the C-terminal of cerebral dopamine neurotrophic factor regulate the protein secretion
Hao Liu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers
Cristiane Latge et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients
Gesine Paul et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Quantitative Analysis of 18F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4′-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease
Patrik Fazio et al.
JOURNAL OF NUCLEAR MEDICINE (2015)
Enhanced Efficacy of the CDNF/MANF Family by Combined Intranigral Overexpression in the 6-OHDA Rat Model of Parkinson's Disease
Oscar Cordero-Llana et al.
MOLECULAR THERAPY (2015)
Proteostasis control by the unfolded protein response
Claudio Hetz et al.
NATURE CELL BIOLOGY (2015)
Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology
Nishant N. Vaikath et al.
NEUROBIOLOGY OF DISEASE (2015)
OBJECTIVE DATA IN PARKINSON'S DISEASE THERAPY MANAGEMENT - A RETROSPECTIVE ANALYSIS OF THE PARKINSON'S KINETIGRAPH (PKG) DATABASE
M. Home et al.
VALUE IN HEALTH (2015)
Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity
K. Matlik et al.
CELL DEATH & DISEASE (2015)
Mechanisms of Anti-inflammatory Property of Conserved Dopamine Neurotrophic Factor: Inhibition of JNK Signaling in Lipopolysaccharide-Induced Microglia
Hua Zhao et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2014)
Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra
Rasajna Nadella et al.
JOURNAL OF NEUROINFLAMMATION (2014)
PERK-Dependent Activation of JAK1 and STAT3 Contributes to Endoplasmic Reticulum Stress-Induced Inflammation
Gordon P. Meares et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
MANF Is Indispensable for the Proliferation and Survival of Pancreatic β Cells
Maria Lindahl et al.
CELL REPORTS (2014)
Glial cell line-derived neurotrophic factor: Characterization of mammalian posttranslational modifications
Elisa Piccinini et al.
ANNALS OF MEDICINE (2013)
Overexpression of conserved dopamine neurotrophic factor (CDNF) in astrocytes alleviates endoplasmic reticulum stress-induced cell damage and inflammatory cytokine secretion
Lei Cheng et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
ER stress-induced cell death mechanisms
Renata Sano et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Disease duration and the integrity of the nigrostriatal system in Parkinson's disease
Jeffrey H. Kordower et al.
BRAIN (2013)
AAV2-mediated striatum delivery of human CDNF prevents the deterioration of midbrain dopamine neurons in a 6-hydroxydopamine induced parkinsonian rat model
Xinmiao Ren et al.
EXPERIMENTAL NEUROLOGY (2013)
Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Secretion and Cell Surface Binding Are Modulated by KDEL Receptors
Mark J. Henderson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Intermittent convection-enhanced delivery to the brain through a novel transcutaneous bone-anchored port
N. U. Barua et al.
JOURNAL OF NEUROSCIENCE METHODS (2013)
Trophic Factor Gene Therapy for Parkinson's Disease
Jeffrey H. Kordower et al.
MOVEMENT DISORDERS (2013)
Targeting the unfolded protein response in disease
Claudio Hetz et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating clinical proof-of-concept for AAV-neurturin (CERE-120) in Parkinson's disease
Raymond T. Bartus et al.
NEUROBIOLOGY OF AGING (2013)
BENEFITS OF PUTAMINAL GDNF INFUSION IN PARKINSON DISEASE ARE MAINTAINED AFTER GDNF CESSATION
Nikunj K. Patel et al.
NEUROLOGY (2013)
Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients
Raymond T. Bartus et al.
NEUROLOGY (2013)
Expression of Human Gaucher Disease Gene GBA Generates Neurodevelopmental Defects and ER Stress in Drosophila Eye
Takahiro Suzuki et al.
PLOS ONE (2013)
GDNF, NGF and BDNF as therapeutic options for neurodegeneration
Shelley J. Allen et al.
PHARMACOLOGY & THERAPEUTICS (2013)
An ERcentric view of Parkinson's disease
Gabriela Mercado et al.
TRENDS IN MOLECULAR MEDICINE (2013)
SorLA Controls Neurotrophic Activity by Sorting of GDNF and Its Receptors GFRα1 and RET
Simon Glerup et al.
CELL REPORTS (2013)
Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease
Susanne Back et al.
BRAIN AND BEHAVIOR (2013)
CDNF Protects the Nigrostriatal Dopamine System and Promotes Recovery After MPTP Treatment in Mice
Mikko Airavaara et al.
CELL TRANSPLANTATION (2012)
The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant -synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins
Cherine Belal et al.
HUMAN MOLECULAR GENETICS (2012)
Mesencephalic Astrocyte-derived Neurotrophic Factor Protects the Heart from Ischemic Damage and Is Selectively Secreted upon Sarco/endoplasmic Reticulum Calcium Depletion
Christopher C. Glembotski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Accumulation of Toxic α-Synuclein Oligomer within Endoplasmic Reticulum Occurs in α-Synucleinopathy In Vivo
Emanuela Colla et al.
JOURNAL OF NEUROSCIENCE (2012)
Endoplasmic Reticulum Stress Is Important for the Manifestations of α-Synucleinopathy In Vivo
Emanuela Colla et al.
JOURNAL OF NEUROSCIENCE (2012)
ER Stress Activates NF-κB by Integrating Functions of Basal IKK Activity, IRE1 and PERK
Arvin B. Tam et al.
PLOS ONE (2012)
α-Synuclein-Induced Down-Regulation of Nurr1 Disrupts GDNF Signaling in Nigral Dopamine Neurons
Mickael Decressac et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson's disease
Mickael Decressac et al.
BRAIN (2011)
Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress
L. Bouman et al.
CELL DEATH AND DIFFERENTIATION (2011)
Neurotrophic factors for the treatment of Parkinson's disease
Aideen M. Sullivan et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2011)
Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease
Merja H. Voutilainen et al.
EXPERIMENTAL NEUROLOGY (2011)
The Endoplasmic Reticulum Stress Sensor, ATF6α, Protects against Neurotoxin-induced Dopaminergic Neuronal Death
Naohiro Egawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
Maarit Hellman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin
Maxim M. Bespalov et al.
JOURNAL OF CELL BIOLOGY (2011)
Intracellular trafficking and secretion of cerebral dopamine neurotrophic factor in neurosecretory cells
Zong-Peng Sun et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson's disease
Arianna Bellucci et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Dysregulated LRRK2 Signaling in Response to Endoplasmic Reticulum Stress Leads to Dopaminergic Neuron Degeneration in C. elegans
Yiyuan Yuan et al.
PLOS ONE (2011)
Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial
William J. Marks et al.
LANCET NEUROLOGY (2010)
ER stress response plays an important role in aggregation of α-synuclein
Peizhou Jiang et al.
MOLECULAR NEURODEGENERATION (2010)
Protective effect against Parkinson's disease-related insults through the activation of XBP1
Megumi Sado et al.
BRAIN RESEARCH (2009)
Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons
Marjo Piltonen et al.
EXPERIMENTAL NEUROLOGY (2009)
Caenorhabditits elegans LRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth
Julia Saermann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Neurorestorative in Rat Model of Parkinson's Disease
Merja H. Voutilainen et al.
JOURNAL OF NEUROSCIENCE (2009)
Translational Control of Long-Lasting Synaptic Plasticity and Memory
Mauro Costa-Mattioli et al.
NEURON (2009)
Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons
Mari Palgi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional
Vimal Parkash et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2009)
Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
William J. Marks et al.
LANCET NEUROLOGY (2008)
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo
Pivi Lindholm et al.
NATURE (2007)
Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal
John T. Slevin et al.
JOURNAL OF NEUROSURGERY (2007)
Activation of the unfolded protein response in Parkinson's disease
J. J. M. Hoozemans et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation
Yasuko Kitao et al.
HUMAN MOLECULAR GENETICS (2007)
Point source concentration of GDNF may explain failure of phase II clinical trial
Michael F. Salvatore et al.
EXPERIMENTAL NEUROLOGY (2006)
α-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
Antony A. Cooper et al.
SCIENCE (2006)
The ASK1-MAP kinase pathways in immune and stress responses
Teruyuki Hayakawa et al.
MICROBES AND INFECTION (2006)
ER stress and neurodegenerative diseases
D Lindholm et al.
CELL DEATH AND DIFFERENTIATION (2006)
Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
AE Lang et al.
ANNALS OF NEUROLOGY (2006)
The diagnosis of Parkinson's disease
E Tolosa et al.
LANCET NEUROLOGY (2006)
Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain
S Love et al.
NATURE MEDICINE (2005)
Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
JT Slevin et al.
JOURNAL OF NEUROSURGERY (2005)
Platelet-derived growth factor (PDGF-BB) and brainderived neurotrophic factor (BDNF) induce striatal neurogenesis in adult rats with 6-hydroxydopamine lesions
P Mohapel et al.
NEUROSCIENCE (2005)
Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease
C Lo Bianco et al.
NEUROBIOLOGY OF DISEASE (2004)
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition
T Yokota et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Neurotrophins and neurodegeneration
D Dawbarn et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2003)
Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons
WA Holtz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
SS Gill et al.
NATURE MEDICINE (2003)
MANF - A new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons
PS Petrova et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2003)
Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
JG Nutt et al.
NEUROLOGY (2003)
Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress
MD Ledesma et al.
JOURNAL OF NEUROCHEMISTRY (2002)
Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys
R Grondin et al.
BRAIN (2002)
The GDNF family: Signalling, biological functions and therapeutic value
MS Airaksinen et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Regulation of cell survival by secreted proneurotrophins
R Lee et al.
SCIENCE (2001)
Heparin coinfusion during convection-enhanced delivery (CED) increases the distribution of the glial-derived neurotrophic factor (GDNF) ligand family in rat striatum and enhances the pharmacological activity of neurturin
JF Hamilton et al.
EXPERIMENTAL NEUROLOGY (2001)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)