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Stefano Biffo et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2018)
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Xiaojing Xia et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2018)
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Srikanth Battu et al.
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Correction: Halofuginone inhibits radiotherapy-induced epithelial-mesenchymal transition in lung cancer
Yang Chen et al.
Oncotarget (2018)
Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy
Alessandra Ferraresi et al.
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The protein restriction mimetic Resveratrol is an autophagy inducer stronger than amino acid starvation in ovarian cancer cells
Alessandra Ferraresi et al.
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Guo-Qing Chen et al.
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Pu Qin et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2017)
Amino acid homeostasis and signalling in mammalian cells and organisms
Stefan Broer et al.
BIOCHEMICAL JOURNAL (2017)
PAT4 levels control amino-acid sensitivity of rapamycin-resistant mTORC1 from the Golgi and affect clinical outcome in colorectal cancer
S-J Fan et al.
ONCOGENE (2016)
CASTORing New Light on Amino Acid Sensing
James E. Hughes Hallett et al.
CELL (2016)
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
Lynne Chantranupong et al.
CELL (2016)
4E-BP1, a multifactor regulated multifunctional protein
Xiaoyu Qin et al.
CELL CYCLE (2016)
Amino Acid Sensing bymTORC1: Intracellular Transporters Mark the Spot
Deborah C. I. Goberdhan et al.
CELL METABOLISM (2016)
Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals
Valerie P. Tan et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Targeting the eIF4F Translation Initiation Complex: A Critical Nexus for Cancer Development
Jerry Pelletier et al.
CANCER RESEARCH (2015)
Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9
Jennifer Jung et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
Autophagy regulation by nutrient signaling
Ryan C. Russell et al.
CELL RESEARCH (2014)
Halofuginone-Induced Amino Acid Starvation Regulates Stat3-Dependent Th17 Effector Function and Reduces Established Autoimmune Inflammation
Thaddeus J. Carlson et al.
JOURNAL OF IMMUNOLOGY (2014)
Translation factors and ribosomal proteins control tumor onset and progression: how?
F. Loreni et al.
ONCOGENE (2014)
The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1
Zhi-Yang Tsun et al.
MOLECULAR CELL (2013)
Signal integration by mTORC1 coordinates nutrient input with biosynthetic output
Christian C. Dibble et al.
NATURE CELL BIOLOGY (2013)
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
Carmine Settembre et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
Wafa B'chir et al.
NUCLEIC ACIDS RESEARCH (2013)
Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway
Jung Min Han et al.
CELL (2012)
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
Carmine Settembre et al.
EMBO JOURNAL (2012)
Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase
Tracy L. Keller et al.
NATURE CHEMICAL BIOLOGY (2012)
Proton-Assisted Amino Acid Transporter PAT1 Complexes with Rag GTPases and Activates TORC1 on Late Endosomal and Lysosomal Membranes
Margret H. Oegmundsdottir et al.
PLOS ONE (2012)
Phase II AIDS Malignancy Consortium Trial of Topical Halofuginone in AIDS-Related Kaposi Sarcoma
Henry B. Koon et al.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2011)
mTOR: from growth signal integration to cancer, diabetes and ageing
Roberto Zoncu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Resveratrol Inhibits Protein Translation in Hepatic Cells
Eugenia Villa-Cuesta et al.
PLOS ONE (2011)
Chelation of Lysosomal Iron Protects Dopaminergic SH-SY5Y Neuroblastoma Cells from Hydrogen Peroxide Toxicity by Precluding Autophagy and Akt Dephosphorylation
Roberta Castino et al.
TOXICOLOGICAL SCIENCES (2011)
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Yasemin Sancak et al.
CELL (2010)
Methods in Mammalian Autophagy Research
Noboru Mizushima et al.
CELL (2010)
Inhibition of PI3k Class III-Dependent Autophagy Prevents Apoptosis and Necrosis by Oxidative Stress in Dopaminergic Neuroblastoma Cells
Roberta Castino et al.
TOXICOLOGICAL SCIENCES (2010)
Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways
Christiane Deval et al.
FEBS JOURNAL (2009)
Control of mammalian gene expression by amino acids, especially glutamine
Carole Brasse-Lagnel et al.
FEBS JOURNAL (2009)
ATF4-dependent transcription mediates signaling of amino acid limitation
Michael S. Kilberg et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
Andrew Y. Choo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes
Nicol F. Trincheri et al.
CARCINOGENESIS (2008)
Coping with stress: eIF2 kinases and translational control
RC Wek et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2006)
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
SJ Marciniak et al.
GENES & DEVELOPMENT (2004)
Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma
A Pines et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2003)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
K Hara et al.
CELL (2002)
MTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
DH Kim et al.
CELL (2002)
Effect of halofuginone on the development of tight skin (TSK) syndrome
T McGaha et al.
AUTOIMMUNITY (2002)