相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Dementia risk and prevention by targeting modifiable vascular risk factors
Sana Tariq et al.
JOURNAL OF NEUROCHEMISTRY (2018)
Co-Administration of TiO2 Nanowired Mesenchymal Stem Cells with Cerebrolysin Potentiates Neprilysin Level and Reduces Brain Pathology in Alzheimer's Disease
Hari Shanker Sharma et al.
MOLECULAR NEUROBIOLOGY (2018)
Idiopathic REM sleep behaviour disorder and neurodegeneration - an update
Birgit Hoegl et al.
NATURE REVIEWS NEUROLOGY (2018)
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
Simon D. Harding et al.
NUCLEIC ACIDS RESEARCH (2018)
Alzheimer's Amyloid-beta is an Antimicrobial Peptide: A Review of the Evidence
Maya L. Gosztyla et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
The Effect of Chronic Cerebral Hypoperfusion on Amyloid-β Metabolism in a Transgenic Mouse Model of Alzheimer's Disease (PS1V97L)
Heyun Yang et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Cerebrospinal Fluid Levels of Angiotensin-Converting Enzyme Are Associated with Amyloid-β42 Burden in Alzheimer's Disease
Natalia P. Rocha et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Targeting Alzheimer's disease with gene and cell therapies
R. Loera-Valencia et al.
JOURNAL OF INTERNAL MEDICINE (2018)
Complex neuroprotective and neurotoxic effects of histone deacetylases
Elizabeth A. Thomas et al.
JOURNAL OF NEUROCHEMISTRY (2018)
Stimulation of ACE2/ANG(1-7)/Mas Axis by Diminazene Ameliorates Alzheimer's Disease in the D-Galactose-Ovariectomized Rat Model: Role of PI3K/Akt Pathway
Ahmed S. Kamel et al.
MOLECULAR NEUROBIOLOGY (2018)
TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
Yingjun Zhao et al.
NEURON (2018)
Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis
D. Adams et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
β-Amyloid accumulation in the human brain after one night of sleep deprivation
Ehsan Shokri-Kojori et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Insulin-Degrading Enzyme in the Fight against Alzheimer's Disease
Igor V. Kurochkin et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Insulin-degrading enzyme is not secreted from cultured cells
Eun Suk Song et al.
SCIENTIFIC REPORTS (2018)
Postsynaptic Proteome of Non-Demented Individuals with Alzheimer's Disease Neuropathology
Olga Zolochevska et al.
JOURNAL OF ALZHEIMERS DISEASE (2018)
Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing
Barry Boland et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Neprilysin inhibition promotes corneal wound healing
Rachel M. Genova et al.
SCIENTIFIC REPORTS (2018)
Self-Reported Sleep Duration and Quality and Cardiovascular Disease and Mortality: A Dose-Response Meta-Analysis
Chun Shing Kwok et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2018)
5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer's disease
Christian Klein et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)
Limited Effects of Prolonged Environmental Enrichment on the Pathology of 5XFAD Mice
Melanie Huettenrauch et al.
MOLECULAR NEUROBIOLOGY (2017)
Long-term neprilysin inhibition - implications for ARNIs
Duncan J. Campbell
NATURE REVIEWS CARDIOLOGY (2017)
Sleep Deprivation Induced Plasma Amyloid-beta Transport Disturbance in Healthy Young Adults
Meng Wei et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
PSD-93 Attenuates Amyloid-beta-Mediated Cognitive Dysfunction by Promoting the Catabolism of Amyloid-beta
Linjie Yu et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Exercise and BDNF reduce Aβ production by enhancing α-secretase processing of APP
Saket M. Nigam et al.
JOURNAL OF NEUROCHEMISTRY (2017)
Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition
Chia-Chen Liu et al.
JOURNAL OF NEUROSCIENCE (2017)
A systemic view of Alzheimer disease - insights from amyloid-β metabolism beyond the brain
Jun Wang et al.
NATURE REVIEWS NEUROLOGY (2017)
EPIGALLOCATECHIN GALLATE INDUCES EXTRACELLULAR DEGRADATION OF AMYLOID β-PROTEIN BY INCREASING NEPRILYSIN SECRETION FROM ASTROCYTES THROUGH ACTIVATION OF ERK AND PI3K PATHWAYS
Naoki Yamamoto et al.
NEUROSCIENCE (2017)
Meta-analysis of expression and function of neprilysin in Alzheimer's disease
Huifeng Zhang et al.
NEUROSCIENCE LETTERS (2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Nuclear hormone receptors
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors
Stephen P. H. Alexander et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Elevated Plasma A42 in Cognitively Impaired Individuals Taking ACE Inhibitor Antihypertensives
William T. Regenold et al.
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2017)
Role of RAGE in Alzheimer's Disease
Zhiyou Cai et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2016)
New Insights into Epigenetic and Pharmacological Regulation of Amyloid-Degrading Enzymes
Natalia N. Nalivaeva et al.
NEUROCHEMICAL RESEARCH (2016)
The activity of blood serum cholinesterases and neprilysin as potential biomarkers of mild-cognitive impairment and Alzheimer’s disease
I. А. Zhuravin et al.
Zhurnal Nevrologii I Psikhiatrii imeni S S Korsakova (2016)
Green tea reduces body fat via upregulation of neprilysin
M. Muenzner et al.
INTERNATIONAL JOURNAL OF OBESITY (2016)
Transthyretin Suppresses Amyloid-β Secretion by Interfering with Processing of the Amyloid-β Protein Precursor
Xinyi Li et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
The association of renin-angiotensin system blockade use with the risks of cognitive impairment of aging and Alzheimer's disease: A meta-analysis
Shan Zhuang et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2016)
The amyloid cascade hypothesis: are we poised for success or failure?
Eric Karran et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes
Jose Morales-Corraliza et al.
JOURNAL OF NEUROSCIENCE (2016)
Major amyloid-β-degrading enzymes, endothelin-converting enzyme-2 and neprilysin, are expressed by distinct populations of GABAergic interneurons in hippocampus and neocortex
Javier Pacheco-Quinto et al.
NEUROBIOLOGY OF AGING (2016)
Mutant Tau knock-in mice display frontotemporal dementia relevant behaviour and histopathology
David J. Koss et al.
NEUROBIOLOGY OF DISEASE (2016)
N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin
A. Ian Smith et al.
SCIENTIFIC REPORTS (2016)
Angiotensin-converting enzyme 2 is reduced in Alzheimer's disease in association with increasing amyloid-β and tau pathology
Patrick Gavin Kehoe et al.
ALZHEIMERS RESEARCH & THERAPY (2016)
Mechanisms of Aβ Clearance and Degradation by Glial Cells
Miriam Ries et al.
FRONTIERS IN AGING NEUROSCIENCE (2016)
Preserved neurogenesis in non-demented individuals with AD neuropathology
David Briley et al.
SCIENTIFIC REPORTS (2016)
Effects of ageing and experimental diabetes on insulin-degrading enzyme expression in male rat tissues
Ekaterina G. Kochkina et al.
BIOGERONTOLOGY (2015)
Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer's Disease
Robert J. Baranello et al.
CURRENT ALZHEIMER RESEARCH (2015)
Sleep Interacts with Aβ to Modulate Intrinsic Neuronal Excitability
Masashi Tabuchi et al.
CURRENT BIOLOGY (2015)
(-)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer's disease model mice by upregulating neprilysin expression
Xiang Chang et al.
EXPERIMENTAL CELL RESEARCH (2015)
Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin
Rajni Parthasarathy et al.
EXPERIMENTAL EYE RESEARCH (2015)
Role of caspase-3 in regulation of the amyloid-degrading neuropeptidase neprilysin level in the rat cortex after hypoxia
D. I. Kozlova et al.
JOURNAL OF EVOLUTIONARY BIOCHEMISTRY AND PHYSIOLOGY (2015)
Hypoxia Affects Neprilysin Expression Through Caspase Activation and an APP Intracellular Domain-dependent Mechanism
Caroline Kerridge et al.
FRONTIERS IN NEUROSCIENCE (2015)
Association between Stroke and Alzheimer's Disease: Systematic Review and Meta-Analysis
Jing Zhou et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
Leptin inhibits amyloid β-protein degradation through decrease of neprilysin expression in primary cultured astrocytes
Naoki Yamamoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β
Simon J. Henderson et al.
BRAIN (2014)
Valproic Acid Reduces Neuritic Plaque Formation and Improves Learning Deficits in APPSwe/PS1A246E Transgenic Mice via Preventing the Prenatal Hypoxia-Induced Down-Regulation of Neprilysin
Zheng Wang et al.
CNS NEUROSCIENCE & THERAPEUTICS (2014)
Sleep in Frontotemporal Dementia is Equally or Possibly More Disrupted, and at an Earlier Stage, When Compared to Sleep in Alzheimer's Disease
Anastasios Bonakis et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Transthyretin Stabilization by Iododiflunisal Promotes Amyloid-beta Peptide Clearance, Decreases its Deposition, and Ameliorates Cognitive Deficits in an Alzheimer's Disease Mouse Model
Carlos A. Ribeiro et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
The Aβ-clearance protein transthyretin, like neprilysin, is epigenetically regulated by the amyloid precursor protein intracellular domain
Caroline Kerridge et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Conversion of Aβ43 to Aβ40 by the Successive Action of Angiotensin-Converting Enzyme 2 and Angiotensin-Converting Enzyme
Shuyu Liu et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2014)
Angiotensin-Neprilysin Inhibition versus Enalapril in Heart Failure
John J. V. McMurray et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models
Mathew Blurton-Jones et al.
STEM CELL RESEARCH & THERAPY (2014)
Amyloid-beta and Alzheimer's disease: the role of neprilysin-2 in amyloid-beta clearance
Robert A. Marr et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
Nonsteroidal Selective Androgen Receptor Modulators and Selective Estrogen Receptor β Agonists Moderate Cognitive Deficits and Amyloid-β Levels in a Mouse Model of Alzheimer's Disease
Sonia George et al.
ACS CHEMICAL NEUROSCIENCE (2013)
Somatostatin receptor subtype-4 agonist NNC 26-9100 mitigates the effect of soluble Aβ42 oligomers via a metalloproteinase-dependent mechanism
Karin E. Sandoval et al.
BRAIN RESEARCH (2013)
Transcriptional Regulation of Insulin-degrading Enzyme Modulates Mitochondrial Amyloid β (Aβ) Peptide Catabolism and Functionality
Maria C. Leal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Endothelin-converting Enzymes Degrade Intracellular β-Amyloid Produced within the Endosomal/Lysosomal Pathway and Autophagosomes
Javier Pacheco-Quinto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The neuroprotector kynurenic acid increases neuronal cell survival through neprilysin induction
Christian Klein et al.
NEUROPHARMACOLOGY (2013)
Intracranial Injection of AAV Expressing NEP but Not IDE Reduces Amyloid Pathology in APP+PS1 Transgenic Mice
Nikisha Carty et al.
PLOS ONE (2013)
Proteolytically Inactive Insulin-Degrading Enzyme Inhibits Amyloid Formation Yielding Non-Neurotoxic Aβ Peptide Aggregates
Matias B. de Tullio et al.
PLOS ONE (2013)
Sleep Drives Metabolite Clearance from the Adult Brain
Lulu Xie et al.
SCIENCE (2013)
Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons
Andrew S. P. Lim et al.
SLEEP (2013)
Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes
Takeshi Katsuda et al.
SCIENTIFIC REPORTS (2013)
Sleep Quality and Preclinical Alzheimer Disease
Yo-El S. Ju et al.
JAMA NEUROLOGY (2013)
Transthyretin is a metallopeptidase with an inducible active site
Marcia A. Liz et al.
BIOCHEMICAL JOURNAL (2012)
Altered NEP2 Expression and Activity in Mild Cognitive Impairment and Alzheimer's Disease
Jeffrey Y. Huang et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Plasma Transthyretin as a Candidate Marker for Alzheimer's Disease
Latha Velayudhan et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Effect of Sodium Valproate Administration on Brain Neprilysin Expression and Memory in Rats
Natalia N. Nalivaeva et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2012)
Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?
Natalia N. Nalivaeva et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid-β1-42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model
Jonathan Brouillette et al.
JOURNAL OF NEUROSCIENCE (2012)
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
Thorlakur Jonsson et al.
NATURE (2012)
Statins in Unconventional Secretion of Insulin-Degrading Enzyme and Degradation of the Amyloid-β Peptide
Konstantin Glebov et al.
NEURODEGENERATIVE DISEASES (2012)
Supercentenarians and transthyretin amyloidosis: The next frontier of human life extension
L. Stephen Coles et al.
PREVENTIVE MEDICINE (2012)
ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models
Paige E. Cramer et al.
SCIENCE (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Endogenous Amyloid-β is Necessary for Hippocampal Synaptic Plasticity and Memory
Daniela Puzzo et al.
ANNALS OF NEUROLOGY (2011)
The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: Characterizing a new regulatory motif
Bryan Maloney et al.
GENE (2011)
Neprilysin, obesity and the metabolic syndrome
K. F. Standeven et al.
INTERNATIONAL JOURNAL OF OBESITY (2011)
gamma-Secretase-Mediated Regulation of Neprilysin: Influence of Cell Density and Aging and Modulation by Imatinib
Charlotte Bauer et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Atrial Fibrillation and Risk of Dementia: A Prospective Cohort Study
Sascha Dublin et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2011)
Preventive and therapeutic types of environmental enrichment counteract beta amyloid pathology by different molecular mechanisms
Arne Herring et al.
NEUROBIOLOGY OF DISEASE (2011)
Amyloid-β Peptide Is a Substrate of the Human 20S Proteasome
Xiaobei Zhao et al.
ACS CHEMICAL NEUROSCIENCE (2010)
Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1ΔE9 mice
Yuan-Shih Hu et al.
FASEB JOURNAL (2010)
Insulin-Degrading Enzyme Sorting in Exosomes: A Secretory Pathway for a Key Brain Amyloid-beta Degrading Protease
Ayelen Bulloj et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
The Transcriptionally Active Amyloid Precursor Protein (APP) Intracellular Domain Is Preferentially Produced from the 695 Isoform of APP in a β-Secretase-dependent Pathway
Nikolai D. Belyaev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Circulating neprilysin clears brain amyloid
Yinxing Liu et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2010)
Decreased Clearance of CNS β-Amyloid in Alzheimer's Disease
Kwasi G. Mawuenyega et al.
SCIENCE (2010)
A PPARdelta Agonist Reduces Amyloid Burden and Brain Inflammation in a Transgenic Mouse Model of Alzheimer's Disease
Sergey Kalinin et al.
CURRENT ALZHEIMER RESEARCH (2009)
Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease
Nikolai D. Belyaev et al.
EMBO REPORTS (2009)
Somatostatin: A Novel Substrate and a Modulator of Insulin-Degrading Enzyme Activity
Chiara Ciaccio et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Estrogen Regulation of the Neprilysin Gene Through A Hormone-Responsive Element
Zhi-Min Xiao et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2009)
Aminopeptidase A contributes to the N-terminal truncation of amyloid β-peptide
Jean Sevalle et al.
JOURNAL OF NEUROCHEMISTRY (2009)
The amyloid hypothesis for Alzheimer's disease: a critical reappraisal
John Hardy
JOURNAL OF NEUROCHEMISTRY (2009)
Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients
Cristian L. Achim et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2009)
Peripherally Expressed Neprilysin Reduces Brain Amyloid Burden: A Novel Approach for Treating Alzheimer's Disease
Hanjun Guan et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
被撤回的出版物: Environmental Experience Modulates Ischemia-Induced Amyloidogenesis and Enhances Functional Recovery (Retracted article. See vol. 32, pg. 863, 2015)
Teresita L. Briones et al.
JOURNAL OF NEUROTRAUMA (2009)
Insulin-degrading enzyme is exported via an unconventional protein secretion pathway
Ji Zhao et al.
MOLECULAR NEURODEGENERATION (2009)
Expression of Neprilysin in Skeletal Muscle Reduces Amyloid Burden in a Transgenic Mouse Model of Alzheimer Disease
Yinxing Liu et al.
MOLECULAR THERAPY (2009)
Minocycline prevents Aβ(25-35)-induced reduction of somatostatin and neprilysin content in rat temporal cortex
E. Burgos-Ramos et al.
LIFE SCIENCES (2009)
Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle
Jae-Eun Kang et al.
SCIENCE (2009)
Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences
Alison R. Whyteside et al.
FEBS LETTERS (2008)
apoE isoform-specific disruption of amyloid β peptide clearance from mouse brain
Rashid Deane et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models
Hong Qing et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Angiotensin-converting enzyme 2 in the brain: properties and future directions
Huijing Xia et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Adeno-associated viral (AAV) serotype 5 vector mediated gene delivery of endothelin-converting enzyme reduces Aβ deposits in APP+PS1 transgenic mice
Niki C. Carty et al.
MOLECULAR THERAPY (2008)
Transthyretin: A key gene involved in the maintenance of memory capacities during aging
Jonathan Brouillette et al.
NEUROBIOLOGY OF AGING (2008)
Aβ inhibits the proteasome and enhances amyloid and tau accumulation
Bertrand P. Tseng et al.
NEUROBIOLOGY OF AGING (2008)
Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, braak stage, and APOE genotype
Edward G. Stopa et al.
STROKE (2008)
Association between neprilysin polymorphisms and sporadic Alzheimer's disease
Linda S. Wood et al.
NEUROSCIENCE LETTERS (2007)
Effects of hypoxia and oxidative stress on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes
Lilia Fisk et al.
NEUROCHEMICAL RESEARCH (2007)
Angiotensin-converting enzyme converts amyloid β-protein 1-42 (Aβ1-42) to Aβ1-40, and its inhibition enhances brain aβ deposition
Kun Zou et al.
JOURNAL OF NEUROSCIENCE (2007)
Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms
David A. Costa et al.
NEUROBIOLOGY OF AGING (2007)
Transport pathways for clearance of human Alzheimer's amyloid β-peptide and apolipoproteins E and J in the mouse central nervous system
Robert D. Bell et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2007)
Does A beta 42 have a function related to blood homeostasis?
John Hardy
NEUROCHEMICAL RESEARCH (2007)
Regulation of steady-state β-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme
Elizabeth A. Eckman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Matrix metalloproteinase-9 degrades amyloid-β fibrils in vitro and compact plaques in situ
Ping Yan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Physiological roles for amyloid β peptides
Hugh A. Pearson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Minocycline affects microglia activation, Aβ deposition, and behavior in APP-tg mice
TJ Seabrook et al.
GLIA (2006)
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
A Rovelet-Lecrux et al.
NATURE GENETICS (2006)
Susceptibility of amyloid β peptide degrading enzymes to oxidative damage:: A potential Alzheimer's disease spiral
H Shinall et al.
BIOCHEMISTRY (2005)
Circulating beta amyloid protein is elevated in patients with acute ischemic stroke
PH Lee et al.
JOURNAL OF NEURAL TRANSMISSION (2005)
Sleep disturbance in mild to moderate Alzheimer's disease
M Moran et al.
SLEEP MEDICINE (2005)
Cerebrospinal fluid neprilysin is reduced in prodromal Alzheimer's disease
M Maruyama et al.
ANNALS OF NEUROLOGY (2005)
Presenilin-dependent transcriptional control of the Aβ-degrading enzyme neprilysin by intracellular domains of βAPP and APLP
R Pardossi-Piquard et al.
NEURON (2005)
Somatostatin regulates brain amyloid β peptide Aβ42 through modulation of proteolytic degradation
T Saito et al.
NATURE MEDICINE (2005)
Environmental enrichment reduces Aβ levels and amyloid deposition in transgenic mice
O Lazarov et al.
CELL (2005)
Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes?
E Steen et al.
JOURNAL OF ALZHEIMERS DISEASE (2005)
Insulin-degrading enzyme in brain microvessels -: Proteolysis of amyloid β vasculotropic variants and reduced activity in cerebral amyloid angiopathy
L Morelli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cerebral ayloid angiopathy and gene polymorphisms
M Yamada
JOURNAL OF THE NEUROLOGICAL SCIENCES (2004)
Systemic catabolism of Alzheimer's Aβ40 and Aβ42
J Ghiso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Minocycline inhibits neuronal death and glial activation induced by β-amyloid peptide in rat hippocampus
JK Ryu et al.
GLIA (2004)
Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer's disease
S Lorenzl et al.
NEUROCHEMISTRY INTERNATIONAL (2003)
Tissue inhibitors of matrix metalloproteinases are elevated in cerebrospinal fluid of neurodegenerative diseases
S Lorenzl et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2003)
Enhancement of neutral endopepticlase activity in SK-N-SH cells by green tea extract
MF Melzig et al.
PHYTOMEDICINE (2003)
ACEH/ACE2 is a novel mammalian metallocarboxypeptidase and a homologue of angiotensin-converting enzyme insensitive to ACE inhibitors
AJ Turner et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2002)
Angiotensin-converting enzyme degrades Alzheimer amyloid β-peptide (Aβ);: Retards Aβ aggregation, deposition, fibril formation, and inhibits cytotoxicity.
JG Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Neprilysin degrades both amyloid β peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases
K Shirotani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Metabolic regulation of brain Aβ by neprilysin
N Iwata et al.
SCIENCE (2001)
Identification and characterization of two androgen response regions in the human neutral endopeptidase gene
RQ Shen et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2000)
A human homolog of angiotensin-converting enzyme - Cloning and functional expression as a captopril-insensitive carboxypeptidase
SR Tipnis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Identification of the major Aβ1-42-degrading catabolic pathway in brain parenchyma:: Suppression leads to biochemical and pathological deposition
N Iwata et al.
NATURE MEDICINE (2000)
分享论文
