In situ laser-induced synthesis of copper-silver microcomposite for enzyme-free D-glucose and L-alanine sensing

In this work, we reported in situ laser-induced synthesis of sensor-active copper-silver microcomposite. This bimetallic microelectrode exhibits highly developed surface area and good electrical conductivity, and can be successfully used for glucose and alanine sensing demonstrating decent sensitivity (31,000 mu A cm(-2) mM(-1) for D-glucose and 11,177 mu A cm(-2) mM(-1) for L-alanine) and low limit of detection (2.8 mu M for D-glucose and 0.83 mu M for L-alanine). High sensor activity and good electrochemical characteristics of the synthesized material can be associated with the eutectic type of the Cu-Ag system. The implemented technique is quite useful for fabrication of new promising small size sensors for enzymeless determination of different biological analytes.