期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 58, 期 29, 页码 9836-9840出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201903668
关键词
azidation; desulfonylative alkynylation; deuteration; diversity-oriented synthesis; radical chemistry
资金
- Deutsche Forschungsgemeinschaft (DFG)
The diversity-oriented desulfonylative functionalization of alkyl allyl sulfones with various sulfone-type reagents by radical chemistry has been developed. The readily installed allylsulfonyl moiety acts as a C-radical precursor, which is substituted by various functionalities using sulfur-based radical trapping reagents. The generality of this approach is documented by the successful desulfonylative alkynylation, azidation, trifluoromethylthiolation, sulfenylation, trifluoromethylselenylation, halogenation, and deuteration. The method is compatible with a wide range of functional groups. Considering the deuteration, products are obtained in good yields with a high level of deuterium incorporation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据