期刊
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
卷 169, 期 3, 页码 482-497出版社
WILEY
DOI: 10.1002/ajpa.23859
关键词
admixture; autosomal DNA; Caribbean; mtDNA; Y-chromosome
资金
- National Cancer Institute (National Institutes of Health) [1K07CA172294]
- National Geographic Society (2012 Geno 2.0 Award)
- Vanderbilt Human Genetics Training Grant (NIH/NIGMS Genetics Predoctoral Research Training Program) [T32GM080178]
- University of Notre Dame
- University of Pennsylvania
Objectives From a genetic perspective, relatively little is known about how mass emigrations of African, European, and Asian peoples beginning in the 16th century affected Indigenous Caribbean populations. Therefore, we explored the impact of serial colonization on the genetic variation of the first Caribbean islanders. Materials and methods Sixty-four members of St. Vincent's Garifuna Community and 36 members of Trinidad's Santa Rosa First People's Community (FPC) of Arima were characterized for mitochondrial DNA and Y-chromosome diversity via direct sequencing and targeted SNP and STR genotyping. A subset of 32 Garifuna and 18 FPC participants were genotyped using the GenoChip 2.0 microarray. The resulting data were used to examine genetic diversity, admixture, and sex biased gene flow in the study communities. Results The Garifuna were most genetically comparable to African descendant populations, whereas the FPC were more similar to admixed American groups. Both communities also exhibited moderate frequencies of Indigenous American matrilines and patrilines. Autosomal SNP analysis indicated modest Indigenous American ancestry in these populations, while both showed varying degrees of African, European, South Asian, and East Asian ancestry, with patterns of sex-biased gene flow differing between the island communities. Discussion These patterns of genetic variation are consistent with historical records of migration, forced, or voluntary, and suggest that different migration events shaped the genetic make-up of each island community. This genomic study is the highest resolution analysis yet conducted with these communities, and provides a fuller understanding of the complex bio-histories of Indigenous Caribbean peoples in the Lesser Antilles.
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