期刊
AMERICAN JOURNAL OF HOSPICE & PALLIATIVE MEDICINE
卷 36, 期 10, 页码 913-926出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1049909119848148
关键词
end of life; advance care planning; goals of care; communication; decision-making; costs; health-care utilization; cancer; systematic review
资金
- Ruth L. Kirschstein National Research Service Award training program in Individualized Care for At Risk Older Adults at the University of Pennsylvania, National Institute of Nursing Research [T32NR009356]
- Rita and Alex Hillman Foundation's Hillman Scholars Program
- Jonas Philanthropies' Jonas Nurse Leaders Scholars program
- National Cancer Institute, National Institutes of Health [R01CA196131]
- National Institute of Nursing Research, National Institutes of Health [R01NR017853]
Background: Aggressive end-of-life (EOL) care is associated with lower quality of life and greater regret about treatment decisions. Higher EOL costs are also associated with lower quality EOL care. Advance care planning and goals-of-care conversations (EOL discussions) may influence EOL health-care utilization and costs among persons with cancer. Objective: To describe associations among EOL discussions, health-care utilization and place of death, and costs in persons with advanced cancer and explore variation in study measures. Methods: A systematic review was conducted using PubMed, Embase, and CINAHL. Twenty quantitative studies published between January 2012 and January 2019 were included. Results: End-of-life discussions are associated with lower health-care costs in the last 30 days of life (median US$1048 vs US$23482; P < .001); lower likelihood of acute care at EOL (odds ratio [(OR] ranging 0.43-0.69); lower likelihood of intensive care at EOL (ORs ranging 0.26-0.68); lower odds of chemotherapy near death (ORs 0.41, 0.57); lower odds of emergency department use and shorter length of hospital stay; greater use of hospice (ORs ranging 1.79 to 6.88); and greater likelihood of death outside the hospital. Earlier EOL discussions (30+ days before death) are more strongly associated with less aggressive care outcomes than conversations occurring near death. Conclusions: End-of-life discussions are associated with less aggressive, less costly EOL care. Clinicians should initiate these discussions with patients having cancer earlier to better align care with preferences.
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