相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy
Jeannie Chew et al.
MOLECULAR NEURODEGENERATION (2019)
Widespread RNA editing dysregulation in brains from autistic individuals
Stephen S. Tran et al.
NATURE NEUROSCIENCE (2019)
Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia
Francesco Paonessa et al.
CELL REPORTS (2019)
ADAR2/miR-589-3p axis controls glioblastoma cell migration/invasion
Valeriana Cesarini et al.
NUCLEIC ACIDS RESEARCH (2018)
Altered editing level of microRNAs is a potential biomarker in lung adenocarcinoma
Keita Maemura et al.
CANCER SCIENCE (2018)
Post-transcriptional regulation of LINE-1 retrotransposition by AID/APOBEC and ADAR deaminases
Elisa Orecchini et al.
CHROMOSOME RESEARCH (2018)
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
Yong-Jie Zhang et al.
NATURE MEDICINE (2018)
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons
Yingxiao Shi et al.
NATURE MEDICINE (2018)
Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies
Wenyan Sun et al.
NATURE NEUROSCIENCE (2018)
C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation
Weiwei Cheng et al.
NATURE COMMUNICATIONS (2018)
C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity
Bhuvaneish T. Selvaraj et al.
NATURE COMMUNICATIONS (2018)
The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer
Phillip M. Shelton et al.
CELL REPORTS (2018)
5-HT2CR antagonist/5-HT2CR inverse agonist recovered the increased isolation-induced aggressive behavior of BALB/c mice mediated by ADAR1 (p110) expression and Htr2c RNA editing
Weizhi Yu et al.
BRAIN AND BEHAVIOR (2018)
Global analysis of A-to-I RNA editing reveals association with common disease variants
Oscar Franzen et al.
PEERJ (2018)
Global Transcriptome Analysis of RNA Abundance Regulation by ADAR in Lung Adenocarcinoma
Michael F. Sharpnack et al.
EBIOMEDICINE (2018)
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease
Bahareh Eftekharzadeh et al.
NEURON (2018)
Kinases of eIF2a Switch Translation of mRNA Subset during Neuronal Plasticity
Ekaterina Chesnokova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development
Mikaela Behm et al.
JOURNAL OF CELL SCIENCE (2017)
Dynamic landscape and regulation of RNA editing in mammals
Meng How Tan et al.
NATURE (2017)
Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport
Fatima Gasset-Rosa et al.
NEURON (2017)
Mutant Huntingtin Disrupts the Nuclear Pore Complex
Jonathan C. Grima et al.
NEURON (2017)
Inside out: the role of nucleocytoplasmic transport in ALS and FTLD
Steven Boeynaems et al.
ACTA NEUROPATHOLOGICA (2016)
PERK-opathies: An Endoplasmic Reticulum Stress Mechanism Underlying Neurodegeneration
Michelle C. Bell et al.
CURRENT ALZHEIMER RESEARCH (2016)
Dynamic regulation of RNA editing in human brain development and disease
Taeyoung Hwang et al.
NATURE NEUROSCIENCE (2016)
The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease
Aaron R. Haeusler et al.
NATURE REVIEWS NEUROSCIENCE (2016)
Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease
Aaron Burberry et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
The AMPA receptor antagonist perampanel robustly rescues amyotrophic lateral sclerosis (ALS) pathology in sporadic ALS model mice
Megumi Akamatsu et al.
SCIENTIFIC REPORTS (2016)
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD
Steven Boeynaems et al.
SCIENTIFIC REPORTS (2016)
C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice
Amanda Atanasio et al.
SCIENTIFIC REPORTS (2016)
Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers
Tania F. Gendron et al.
ACTA NEUROPATHOLOGICA (2015)
FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions
Dejun Yang et al.
ACTA NEUROPATHOLOGICA (2015)
Isoform-Specific Antibodies Reveal Distinct Subcellular Localizations of C9orf72 in Amyotrophic Lateral Sclerosis
Shangxi Xiao et al.
ANNALS OF NEUROLOGY (2015)
The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
Ke Zhang et al.
NATURE (2015)
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
Brian D. Freibaum et al.
NATURE (2015)
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
Ana Jovicic et al.
NATURE NEUROSCIENCE (2015)
Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS
Helene Tran et al.
NEURON (2015)
Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress
Yong-Jie Zhang et al.
ACTA NEUROPATHOLOGICA (2014)
C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration
Stephanie May et al.
ACTA NEUROPATHOLOGICA (2014)
RNA-protein interactions in unstable microsatellite diseases
Apoorva Mohan et al.
BRAIN RESEARCH (2014)
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
Claudio Hetz et al.
NATURE REVIEWS NEUROSCIENCE (2014)
PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease
Latha Devi et al.
NEUROBIOLOGY OF AGING (2014)
Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion
Adrian J. Waite et al.
NEUROBIOLOGY OF AGING (2014)
Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
Xinmei Wen et al.
NEURON (2014)
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
Sarah Mizielinska et al.
SCIENCE (2014)
Advances in treating amyotrophic lateral sclerosis: insights from pathophysiological studies
Steve Vucic et al.
TRENDS IN NEUROSCIENCES (2014)
Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood
Veronique V. Belzil et al.
ACTA NEUROPATHOLOGICA (2013)
Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons
Sandra Almeida et al.
ACTA NEUROPATHOLOGICA (2013)
Loss of Function of C9orf72 Causes Motor Deficits in a Zebrafish Model of Amyotrophic Lateral Sclerosis
Sorana Ciura et al.
ANNALS OF NEUROLOGY (2013)
Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
Peter E. A. Ash et al.
NEURON (2013)
RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
Christopher J. Donnelly et al.
NEURON (2013)
Deletion of C9ORF72 Results in Motor Neuron Degeneration and Stress Sensitivity in C-elegans
Martine Therrien et al.
PLOS ONE (2013)
RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia
Tao Zu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
Clotilde Lagier-Tourenne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS
Kohji Mori et al.
SCIENCE (2013)
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
Dhruv Sareen et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
Youn-Bok Lee et al.
CELL REPORTS (2013)
A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study
Ilse Gijselinck et al.
LANCET NEUROLOGY (2012)
Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons
Takuto Hideyama et al.
NEUROBIOLOGY OF DISEASE (2012)
Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response
Christian K. Pfaller et al.
CURRENT OPINION IN IMMUNOLOGY (2011)
Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
Mariely DeJesus-Hernandez et al.
NEURON (2011)
A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
Alan E. Renton et al.
NEURON (2011)
Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2
Takuto Hideyama et al.
JOURNAL OF NEUROSCIENCE (2010)
The mechanism of eukaryotic translation initiation and principles of its regulation
Richard J. Jackson et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Transfection of mammalian cells using linear polyethylenimine is a simple and effective means of producing recombinant adeno-associated virus vectors
Sharon E. Reed et al.
JOURNAL OF VIROLOGICAL METHODS (2006)
Deficient RNA editing of GluR2 and neuronal death in amyotropic lateral sclerosis
S Kwak et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2005)
Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1
JC Hartner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene
QD Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis
Q Wang et al.
SCIENCE (2000)
Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2
M Higuchi et al.
NATURE (2000)
A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains
CX Chen et al.
RNA (2000)
分享论文
