期刊
CELLS
卷 8, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/cells8040287
关键词
mitochondrial biogenesis; ROS; cAMP signaling; yeast
类别
资金
- Ligue contre le Cancer
- Agence Nationale de la Recherche
- CNRS (Conseil National de la Recherche Scientifique)
Mitochondrial biogenesis is a complex process. It requires the contribution of both the nuclear and the mitochondrial genomes and therefore cross talk between the nucleus and mitochondria. Cellular energy demand can vary by great length and it is now well known that one way to adjust adenosine triphosphate (ATP) synthesis to energy demand is through modulation of mitochondrial content in eukaryotes. The knowledge of actors and signals regulating mitochondrial biogenesis is thus of high importance. Here, we review the regulation of mitochondrial biogenesis both in yeast and in mammalian cells through mitochondrial reactive oxygen species.
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