相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Regulation of axonal EphA4 forward signaling is involved in the effect of EphA3 on chicken retinal ganglion cell axon growth during retinotectal mapping
Luciano Fiore et al.
EXPERIMENTAL EYE RESEARCH (2019)
ARHGEF19 interacts with BRAF to activate MAPK signaling during the tumorigenesis of non-small cell lung cancer
Yingchang Li et al.
INTERNATIONAL JOURNAL OF CANCER (2018)
Tale of the Good and the Bad Cdk5: Remodeling of the Actin Cytoskeleton in the Brain
Kavita Shah et al.
MOLECULAR NEUROBIOLOGY (2018)
Eph Receptor Effector Ephexin Mediates Olfactory Dendrite Targeting in Drosophila
Juhi Sardana et al.
DEVELOPMENTAL NEUROBIOLOGY (2018)
Characterization of germline mutations in familial lung cancer from the Chinese population
Madiha Kanwal et al.
GENE (2018)
Ephrin-A1-EphA4 signaling negatively regulates myelination in the central nervous system
Mette Harboe et al.
GLIA (2018)
Ephexin1 Is Required for Eph-Mediated Limb Trajectory of Spinal Motor Axons
Chih-Ju Chang et al.
JOURNAL OF NEUROSCIENCE (2018)
Mechanisms of RhoA inactivation and CDC42 and Rac1 activation during zebrafish optic nerve regeneration
Toru Matsukawa et al.
NEUROCHEMISTRY INTERNATIONAL (2018)
GLI2 promotes cell proliferation and migration through transcriptional activation of ARHGEF16 in human glioma cells
Dengliang Huang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
The Intermolecular Interaction of Ephexin4 Leads to Autoinhibition by Impeding Binding of RhoG
Kwanhyeong Kim et al.
CELLS (2018)
Critical role of EphA4 in early brain injury after subarachnoid hemorrhage in rat
Ruiming Fan et al.
EXPERIMENTAL NEUROLOGY (2017)
The Evolutionary Landscape of Dbl-Like RhoGEF Families: Adapting Eukaryotic Cells to Environmental Signals
Philippe Fort et al.
GENOME BIOLOGY AND EVOLUTION (2017)
Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer's-like impairment in mice
Gabrielle L. Sell et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
A dual role for the RhoGEF Ephexin5 in regulation of dentritic spine outgrowth
A. M. Hamilton et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2017)
Increased EphA4-ephexin1 signaling in the medial prefrontal cortex plays a role in depression-like phenotype
Ji-chun Zhang et al.
SCIENTIFIC REPORTS (2017)
Intermolecular steric inhibition of Ephexin4 is relieved by Elmo1
Kwanhyeong Kim et al.
SCIENTIFIC REPORTS (2017)
ARHGEF15 overexpression worsens the prognosis in patients with pancreatic ductal adenocarcinoma through enhancing the motility and proliferative activity of the cancer cells
Hiroto Fukushima et al.
MOLECULAR CANCER (2016)
Regulating Rho GTPases and their regulators
Richard G. Hodge et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
The Rho guanine nucleotide exchange factor ARHGEF5 promotes tumor malignancy via epithelial-mesenchymal transition
Y. Komiya et al.
ONCOGENESIS (2016)
Targeting rho guanine nucleotide exchange factor ARHGEF5/TIM with auto-inhibitory peptides in human breast cancer
Ou Huang et al.
AMINO ACIDS (2015)
The auto-inhibitory state of Rho guanine nucleotide exchange factor ARHGEF5/TIM can be relieved by targeting its SH3 domain with rationally designed peptide aptamers
Ping He et al.
BIOCHIMIE (2015)
Rho Guanine Nucleotide Exchange Factor 5 Increases Lung Cancer Cell Tumorigenesis via MMP-2 and Cyclin D1 Upregulation
Ping He et al.
MOLECULAR CANCER THERAPEUTICS (2015)
Endothelial RhoGEFs: A systematic analysis of their expression profiles in VEGF-stimulated and tumor endothelial cells
Ricardo Hernandez-Garcia et al.
VASCULAR PHARMACOLOGY (2015)
Arhgef16, a novel Elmo1 binding partner, promotes clearance of apoptotic cells via RhoG-dependent Rac1 activation
Juyeon Lee et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
EphB6 promotes anoikis by modulating EphA2 signaling
Mai Akada et al.
CELLULAR SIGNALLING (2014)
Dock-family exchange factors in cell migration and disease
Gilles Gadea et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2014)
miR-503 regulates metastatic function through Rho guanine nucleotide exchanger factor 19 in hepatocellular carcinoma
Jing Zhou et al.
JOURNAL OF SURGICAL RESEARCH (2014)
Long-term treatment with PP2 after spinal cord injury resulted in functional locomotor recovery and increased spared tissue
Odrick R. Rosas et al.
NEURAL REGENERATION RESEARCH (2014)
I'm coming to GEF you Regulation of RhoGEFs during cell migration
Silvia M. Goicoechea et al.
CELL ADHESION & MIGRATION (2014)
Exome sequencing reveals new causal mutations in children with epileptic encephalopathies
Krishna R. Veeramah et al.
EPILEPSIA (2013)
Deciphering the Molecular and Functional Basis of Dbl Family Proteins A NOVEL SYSTEMATIC APPROACH TOWARD CLASSIFICATION OF SELECTIVE ACTIVATION OF THE Rho FAMILY PROTEINS
Mamta Jaiswal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Co-expression of Rho guanine nucleotide exchange factor 5 and Src associates with poor prognosis of patients with resected non-small cell lung cancer
Ping He et al.
ONCOLOGY REPORTS (2013)
Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells
Jean Defourny et al.
NATURE COMMUNICATIONS (2013)
Ephexin4-mediated promotion of cell migration and anoikis resistance is regulated by serine 897 phosphorylation of EphA2
Hiromu Kawai et al.
FEBS OPEN BIO (2013)
Rho family GTPases
Alan Hall
BIOCHEMICAL SOCIETY TRANSACTIONS (2012)
TGF-β-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A
Hajime Mihira et al.
JOURNAL OF BIOCHEMISTRY (2012)
The Ras protein superfamily: Evolutionary tree and role of conserved amino acids
Ana Maria Rojas et al.
JOURNAL OF CELL BIOLOGY (2012)
Arhgef15 Promotes Retinal Angiogenesis by Mediating VEGF-Induced Cdc42 Activation and Potentiating RhoJ Inactivation in Endothelial Cells
Sentaro Kusuhara et al.
PLOS ONE (2012)
The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42
A. W. Oliver et al.
BRITISH JOURNAL OF CANCER (2011)
Expression and Activation of Ephexin Is Altered After Spinal Cord Injury
Odrick R. Rosas et al.
DEVELOPMENTAL NEUROBIOLOGY (2011)
Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase
Kohei Harada et al.
EXPERIMENTAL CELL RESEARCH (2011)
The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation
Miho Kuroiwa et al.
JOURNAL OF CELL SCIENCE (2011)
Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice
Yoko Fukushima et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Pronephric Tubulogenesis Requires Daam1-Mediated Planar Cell Polarity Signaling
Rachel K. Miller et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)
Absence of Common Somatic Alterations in Genes on 1p and 19q in Oligodendrogliomas
Linda B. Bralten et al.
PLOS ONE (2011)
Ephecting Excitatory Synapse Development
Matthew B. Dalva
CELL (2010)
EphB-Mediated Degradation of the RhoA GEF Ephexin5 Relieves a Developmental Brake on Excitatory Synapse Formation
Seth S. Margolis et al.
CELL (2010)
Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism
Nao Hiramoto-Yamaki et al.
JOURNAL OF CELL BIOLOGY (2010)
Ephexin1 Is Required for Structural Maturation and Neurotransmission at the Neuromuscular Junction
Lei Shi et al.
NEURON (2010)
Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies
L. Hampson et al.
BRITISH JOURNAL OF CANCER (2009)
Regulation of Immature Dendritic Cell Migration by RhoA Guanine Nucleotide Exchange Factor Arhgef5
Zhenglong Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
A Presynaptic Homeostatic Signaling System Composed of the Eph Receptor, Ephexin, Cdc42, and CaV2.1 Calcium Channels
C. Andrew Frank et al.
NEURON (2009)
Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteins
Marielle E. Yohe et al.
BIOCHEMISTRY (2008)
WGEF activates Rho in the Wnt-PCP pathway and controls convergent extension in Xenopus gastrulation
Kosuke Tanegashima et al.
EMBO JOURNAL (2008)
Engulfment of apoptotic cells: signals for a good meal
Kodi S. Ravichandran et al.
NATURE REVIEWS IMMUNOLOGY (2007)
GEFs and GAPs: Critical elements in the control of small G proteins
Johannes L. Bos et al.
CELL (2007)
Auto-inhibition of the Dbl family protein tim by an N-terminal helical motif
Marielle E. Yohe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Bidirectional Eph-ephrin signaling during axon guidance
Joaquim Egea et al.
TRENDS IN CELL BIOLOGY (2007)
Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism
Wing-Yu Fu et al.
NATURE NEUROSCIENCE (2007)
Toxicogenomics of kojic acid on gene expression profiling of A375 human malignant melanoma cells
SL Cheng et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2006)
Regulation of EphA4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function
J Egea et al.
NEURON (2005)
Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse
M Sahin et al.
NEURON (2005)
TIM, a Dbl-related protein, regulates cell shape and cytoskeletal organization in a Rho-dependent manner
XZ Xie et al.
CELLULAR SIGNALLING (2005)
GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
KL Rossman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Expression and molecular characterization of alternative transcripts of the ARHGEF5/TIM oncogene specific for human breast cancer
MA Debily et al.
HUMAN MOLECULAR GENETICS (2004)
Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38
L Lamalice et al.
ONCOGENE (2004)
WGEF is a novel RhoGEF expressed in intestine, liver, heart, and kidney
YH Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
EphA4-mediated rho activation via Vsm-RhoGEF expressed specifically in vascular smooth muscle cells
H Ogita et al.
CIRCULATION RESEARCH (2003)
Rho GTPases in cell biology
S Etienne-Manneville et al.
NATURE (2002)
Mechanisms and functions of EPH and ephrin signalling
K Kullander et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
The role of Rho GTPases in disease development
B Boettner et al.
GENE (2002)
EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin
SM Shamah et al.
CELL (2001)
Characterization of Ngef, a novel member of the Dbl family of genes expressed predominantly in the caudate nucleus
NR Rodrigues et al.
GENOMICS (2000)