相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Intercellualar Communication between Airway Epithelial Cells Is Mediated by Exosome-Like Vesicles
Richa Gupta et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2019)
Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways
Kent Miner et al.
FRONTIERS IN PHARMACOLOGY (2019)
Redox biology of regulated cell death in cancer: A focus on necroptosis and ferroptosis
Cristina Florean et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Different immunohistochemical localization for TMEM16A and CFTR in acinar and ductal cells of rat major salivary glands and exocrine pancreas
Takuya Yokoyama et al.
ACTA HISTOCHEMICA (2019)
TMEM16A is indispensable for basal mucus secretion in airways and intestine
Roberta Benedetto et al.
FASEB JOURNAL (2019)
Matrine is a novel inhibitor of the TMEM16A chloride channel with antilung adenocarcinoma effects
Shuai Guo et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Lipid Peroxidation Drives Renal Cyst Growth In Vitro through Activation of TMEM16A
Rainer Schreiber et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2019)
Chemically induced vesiculation as a platform for studying TMEM16F activity
Tina W. Han et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Niclosamide Induces Cell Cycle Arrest in G1 Phase in Head and Neck Squamous Cell Carcinoma Through Let-7d/CDC34 Axis
Zewen Han et al.
FRONTIERS IN PHARMACOLOGY (2019)
TMEM16F activation by Ca2+ triggers plasma membrane expansion and directs PD-1 trafficking
Christopher Bricogne et al.
SCIENTIFIC REPORTS (2019)
ADAM10 sheddase activation is controlled by cell membrane asymmetry
Florian Bleibaum et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2019)
Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca2+ and plasma membrane lipid
Rainer Schreiber et al.
JOURNAL OF PHYSIOLOGY-LONDON (2018)
CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6)
Filipa Simoes et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2018)
Activation of Anoctamin-1 Limits Pulmonary Endothelial Cell Proliferation via p38-Mitogen-activated Protein Kinase-Dependent Apoptosis
Ayed M. Allawzi et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2018)
Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial
Susen Burock et al.
BMC CANCER (2018)
Transmembrane member 16A participates in hydrogen peroxide-induced apoptosis by facilitating mitochondria-dependent pathway in vascular smooth muscle cells
Jia-Wei Zeng et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Transcriptional repression of human epidermal growth factor receptor 2 by ClC-3 Cl-/H+ transporter inhibition in human breast cancer cells
Mayu Fujimoto et al.
CANCER SCIENCE (2018)
Anoctamin 9/TMEM16J is a cation channel activated by cAMP/PKA signal
Hyungsup Kim et al.
CELL CALCIUM (2018)
A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer
Michael T. Schweizer et al.
PLOS ONE (2018)
Single-molecule analysis of phospholipid scrambling by TMEM16F
Rikiya Watanabe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Contribution of TMEM16F to pyroptotic cell death
Jiraporn Ousingsawat et al.
CELL DEATH & DISEASE (2018)
Inhibition of ANO1/TMEM16A induces apoptosis in human prostate carcinoma cells by activating TNF-alpha signaling
Yan Song et al.
CELL DEATH & DISEASE (2018)
Calcium-activated chloride channels clamp odor-evoked spike activity in olfactory receptor neurons
Joseph D. Zak et al.
SCIENTIFIC REPORTS (2018)
Anoctamin-6 regulates ADAM sheddase function
Martin Veit et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2018)
Notch Signaling in the Tumor Microenvironment
Olivier Meurette et al.
CANCER CELL (2018)
ANO7 is associated with aggressive prostate cancer
Elina Kaikkonen et al.
INTERNATIONAL JOURNAL OF CANCER (2018)
Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium
Haider H. Dar et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Anoctamin 5/TMEM16E facilitates muscle precursor cell fusion
Jarred M. Whitlock et al.
JOURNAL OF GENERAL PHYSIOLOGY (2018)
Structure of a volume-regulated anion channel of the LRRC8 family
Dawid Deneka et al.
NATURE (2018)
Cryo-EM structures of the human volume-regulated anion channel LRRC8
Go Kasuya et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)
Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase
Byoung-Cheol Lee et al.
NATURE COMMUNICATIONS (2018)
The Antihelminthic Niclosamide Inhibits Cancer Stemness, Extracellular Matrix Remodeling, and Metastasis through Dysregulation of the Nuclear β-catenin/c-Myc axis in OSCC
Lin-Hong Wang et al.
SCIENTIFIC REPORTS (2018)
Structure of the human volume regulated anion channel
Jennifer M. Kefauver et al.
ELIFE (2018)
Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors
Yohan Seo et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer
Naveed Ishaque et al.
NATURE COMMUNICATIONS (2018)
Gain of function of TMEM16E/ANO5 scrambling activity caused by a mutation associated with gnathodiaphyseal dysplasia
Eleonora Di Zanni et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice
Jianqiang Bao et al.
JCI INSIGHT (2018)
Nephron-specific knockout of TMEM16A leads to reduced number of glomeruli and albuminuria
Laura K. Schenk et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2018)
Oncogenic Ras Isoforms Signaling Specificity at the Membrane
Ruth Nussinov et al.
CANCER RESEARCH (2018)
Current knowledge on exosome biogenesis and release
Nina Pettersen Hessvik et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Ca2+ signals, cell membrane disintegration, and activation of TMEM16F during necroptosis
Jiraporn Ousingsawat et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
Anoctamin2 (TMEMI6B) forms the Ca2+-activated Cl- channel in the retinal pigment epithelium
Susanne Keckeis et al.
EXPERIMENTAL EYE RESEARCH (2017)
Activation of a Ca2+-dependent cation conductance with properties of TRPM2 by reactive oxygen species in lens epithelial cells
Susanne Keckeis et al.
EXPERIMENTAL EYE RESEARCH (2017)
Differential effects of anoctamins on intracellular calcium signals
Ines Cabrita et al.
FASEB JOURNAL (2017)
Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling
Bin Chen et al.
GASTROENTEROLOGY (2017)
Anoctamin5 regulates cell migration and invasion in thyroid cancer
Zhengyan Chang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2017)
Leucine-rich repeat-containing 8B protein is associated with the endoplasmic reticulum Ca2+ leak in HEK293 cells
Arijita Ghosh et al.
JOURNAL OF CELL SCIENCE (2017)
MicroRNA-381 inhibits the metastasis of gastric cancer by targeting TMEM16A expression
Qinghua Cao et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)
Ion channel signaling influences cellular proliferation and phagocyte activity during axolotl tail regeneration
Brandon M. Franklin et al.
MECHANISMS OF DEVELOPMENT (2017)
Cell-specific mechanisms of TMEM16A Ca2+-activated chloride channel in cancer
Hui Wang et al.
MOLECULAR CANCER (2017)
Suppression of the Growth and Invasion of Human Head and Neck Squamous Cell Carcinomas via Regulating STAT3 Signaling and the miR-21/β-catenin Axis with HJC0152
Yu Wang et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM
Cristina Paulino et al.
NATURE (2017)
Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis
Mu He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Pulses of Ca2+ coordinate actin assembly and exocytosis for stepwise cell extension
Norio Takeshita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Characterization of the scrambling domain of the TMEM16 family
Sayuri Gyobu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Cell-specific regulation of proliferation by Ano1/TMEM16A in breast cancer with different ER, PR, and HER2 status
Huizhe Wu et al.
ONCOTARGET (2017)
Anti-helminthic niclosamide inhibits Ras-driven oncogenic transformation via activation of GSK-3
Sung Yong Ahn et al.
ONCOTARGET (2017)
Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
Cristina Paulino et al.
ELIFE (2017)
Inhibition of ANO1 by luteolin and its cytotoxicity in human prostate cancer PC-3 cells
Yohan Seo et al.
PLOS ONE (2017)
Epithelial Chloride Transport by CFTR Requires TMEM16A
Roberta Benedetto et al.
SCIENTIFIC REPORTS (2017)
TMEM16A/ANO1 Inhibits Apoptosis Via Downregulation of Bim Expression
Neal R. Godse et al.
CLINICAL CANCER RESEARCH (2017)
ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancer
Ikhyun Jun et al.
BRITISH JOURNAL OF CANCER (2017)
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease
Brent R. Stockwell et al.
CELL (2017)
Expression of anoctamin 1 is associated with advanced tumor stage in patients with non-small cell lung cancer and predicts recurrence after surgery
Y. He et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2017)
Chloride ion transport and overexpression of TMEM16A in a guinea-pig asthma model
M. Kondo et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2017)
TMEM16A exacerbates renal injury by activating P38/JNK signaling pathway to promote podocyte apoptosis in diabetic nephropathy mice
Huan Lian et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences
Yi-Nan Gong et al.
CELL (2017)
Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine
John Malysz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2017)
Cellular defects by deletion of ANO10 are due to deregulated local calcium signaling
Podchanart Wanitchakool et al.
CELLULAR SIGNALLING (2017)
Transcriptional repression of HER2 by ANO1 Cl- channel inhibition in human breast cancer cells with resistance to trastuzumab
Mayu Fujimoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
A Role of TMEM16E Carrying a Scrambling Domain in Sperm Motility
Sayuri Gyobu et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
Cellular volume regulation by anoctamin 6: Ca2+, phospholipase A2 and osmosensing
Lalida Sirianant et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
Modulating Ca2+ signals: a common theme for TMEM16, Ist2, and TMC
Karl Kunzelmann et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
Anoctamin 1 (Ano1) is required for glucose-induced membrane potential oscillations and insulin secretion by murine β-cells
Raphael Crutzen et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against Cisplatin-induced expression of p53, MDM2, p21Waf1/Cip1, and Caspase-9/-3 activation
Belinda Halling Sorensen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)
Ion channels in regulated cell death
Karl Kunzelmann
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Transition from inflammation to proliferation: a critical step during wound healing
Ning Xu Landen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Novel Use for DOG1 in Discriminating Breast Invasive Carcinoma from Noninvasive Breast Lesions
Henghui Cheng et al.
DISEASE MARKERS (2016)
Cl- channels in apoptosis
Podchanart Wanitchakool et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2016)
Survival protein anoctamin-6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage
Nadine J. A. Mattheij et al.
FASEB JOURNAL (2016)
Coupling of TRPV6 and TMEM16A in epithelial principal cells of the rat epididymis
Da Yuan Gao et al.
JOURNAL OF GENERAL PHYSIOLOGY (2016)
Integrated Genetic, Epigenetic, and Transcriptional Profiling Identifies Molecular Pathways in the Development of Laterally Spreading Tumors
Luke B. Hesson et al.
MOLECULAR CANCER RESEARCH (2016)
Non-essential contribution of LRRC8A to volume regulation
Lalida Sirianant et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
Expression of anoctamins in retinal pigment epithelium (RPE)
Rainer Schreiber et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
Relationship between TMEM16A/anoctamin 1 and LRRC8A
Roberta Benedetto et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
Biophysics and Physiology of the Volume-Regulated Anion Channel (VRAC)/Volume-Sensitive Outwardly Rectifying Anion Channel (VSOR)
Stine F. Pedersen et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2016)
Phosphatidylserine exposure is required for ADAM17 sheddase function
Anselm Sommer et al.
NATURE COMMUNICATIONS (2016)
Inhibition of calcium-activated chloride channel ANO1 suppresses proliferation and induces apoptosis of epithelium originated cancer cells
Lizhao Guan et al.
ONCOTARGET (2016)
ANO1 protein as a potential biomarker for esophageal cancer prognosis and precancerous lesion development prediction
Li Shang et al.
ONCOTARGET (2016)
Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer
Rebecca C. Arend et al.
ONCOTARGET (2016)
Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells
Young-Sun Lee et al.
SCIENTIFIC REPORTS (2016)
Activation of Ca2+-activated Cl- channel ANO1 by localized Ca2+ signals
Xin Jin et al.
JOURNAL OF PHYSIOLOGY-LONDON (2016)
Meta-Analyses of Microarray Datasets Identifies ANO1 and FADD as Prognostic Markers of Head and Neck Cancer
Ram Bhupal Reddy et al.
PLOS ONE (2016)
The Redox Status of Cancer Cells Supports Mechanisms behind the Warburg Effect
Jorgelindo da Veiga Moreira et al.
METABOLITES (2016)
Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish
Toshiki Yamada et al.
PHYSIOLOGICAL REPORTS (2016)
The identification of a volume-regulated anion channel: an amazing Odyssey
S. F. Pedersen et al.
ACTA PHYSIOLOGICA (2015)
Aberrant expressions of c-KIT and DOG-1 in mucinous and nonmucinous colorectal carcinomas and relation to clinicopathologic features and prognosis
Abd Al-Rahman Mohammad Foda et al.
ANNALS OF DIAGNOSTIC PATHOLOGY (2015)
Study of NGEP expression pattern in cancerous tissues provides novel insights into prognostic marker in prostate cancer
Monireh Mohsenzadegan et al.
BIOMARKERS IN MEDICINE (2015)
Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs
Rosa Planells-Cases et al.
EMBO JOURNAL (2015)
Anoctamin-6 Controls Bone Mineralization by Activating the Calcium Transporter NCX1
Jiraporn Ousingsawat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity
Christian Hammer et al.
MOLECULAR MEDICINE (2015)
Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung
Daniel Lafkas et al.
NATURE (2015)
Inhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell Lines
Yohan Seo et al.
PLOS ONE (2015)
Ano1/TMEM16A Overexpression Is Associated with Good Prognosis in PR-Positive or HER2-Negative Breast Cancer Patients following Tamoxifen Treatment
Huizhe Wu et al.
PLOS ONE (2015)
Bestrophin 1 is indispensable for volume regulation in human retinal pigment epithelium cells
Andrea Milenkovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
TMEM16, LRRC8A, bestrophin: chloride channels controlled by Ca2+ and cell volume
Karl Kunzelmann
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation
V. Forschbach et al.
CELL DEATH & DISEASE (2015)
Anoctamin 6 mediates effects essential for innate immunity downstream of P2X7 receptors in macrophages
Jiraporn Ousingsawat et al.
NATURE COMMUNICATIONS (2015)
Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B
Jie Zheng et al.
ONCOTARGET (2015)
ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer
Anke Bill et al.
ONCOTARGET (2015)
Identification and characterization of ANO9 in stage II and III colorectal carcinoma
Chunxiang Li et al.
ONCOTARGET (2015)
Clinical significance of Anoctamin-1 gene at 11q13 in the development and progression of head and neck squamous cell carcinomas
Juan P. Rodrigo et al.
SCIENTIFIC REPORTS (2015)
TMEM16A/ANO1 is differentially expressed in HPV-negative versus HPV-positive head and neck squamous cell carcinoma through promoter methylation
Ronak Dixit et al.
SCIENTIFIC REPORTS (2015)
Notch2 Is Required for Inflammatory Cytokine-Driven Goblet Cell Metaplasia in the Lung
Henry Danahay et al.
CELL REPORTS (2015)
Secreted CLCA1 modulates TMEM16A to activate Ca2+-dependent chloride currents in human cells
Monica Sala-Rabanal et al.
ELIFE (2015)
Co-expression of Anoctamins in Cilia of Olfactory Sensory Neurons
Bastian Henkel et al.
CHEMICAL SENSES (2015)
ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)
D. R. P. Sauter et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)
Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine
Rainer Schreiber et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)
Exome Analysis Reveals Differentially Mutated Gene Signatures of Stage, Grade and Subtype in Breast Cancers
You Li et al.
PLOS ONE (2015)
Upregulation of TMEM16A Protein in Bronchial Epithelial Cells by Bacterial Pyocyanin
Emanuela Caci et al.
PLOS ONE (2015)
Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung Cancer
Linghan Jia et al.
PLOS ONE (2015)
Identification of the Novel TMEM16A Inhibitor Dehydroandrographolide and Its Anticancer Activity on SW620 Cells
Yujie Sui et al.
PLOS ONE (2015)
TMEM16A is a Ca2+-activated Cl- channel expressed in the renal collecting duct
P. Svenningsen et al.
ACTA PHYSIOLOGICA (2014)
The role of MAPK signalling pathways in the response to endoplasmic reticulum stress
Nicola J. Darling et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells
Anna Edlund et al.
BMC MEDICINE (2014)
Multi-targeted therapy of cancer by niclosamide: A new application for an old drug
Yonghe Li et al.
CANCER LETTERS (2014)
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
Zhaozhu Qiu et al.
CELL (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
TMC8 (EVER2) attenuates intracellular signaling by Zn2+ and Ca2+ and suppresses activation of Cl- currents
Lalida Sirianant et al.
CELLULAR SIGNALLING (2014)
Chloride secretion, anoctamin 1 and Ca2+ signaling
Karl Kunzelmann et al.
CHANNELS (2014)
Niclosamide Inhibits Androgen Receptor Variants Expression and Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer
Chengfei Liu et al.
CLINICAL CANCER RESEARCH (2014)
Functional role of the Ca2+-activated Cl- channel DOG1/TMEM16A in gastrointestinal stromal tumor cells
Erik Berglund et al.
EXPERIMENTAL CELL RESEARCH (2014)
Simvastatin Potently Induces Calcium-dependent Apoptosis of Human Leiomyoma Cells
Mostafa A. Borahay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function
Lalit Kumar et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells
Bjoern Buchholz et al.
KIDNEY INTERNATIONAL (2014)
The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function
Diana Faria et al.
KIDNEY INTERNATIONAL (2014)
The Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesis
Chelsey Chandler Ruppersburg et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Transmembrane protein with unknown function 16A overexpression promotes glioma formation through the nuclear factor-.B signaling pathway
Jun Liu et al.
MOLECULAR MEDICINE REPORTS (2014)
X-ray structure of a calcium-activated TMEM16 lipid scramblase
Janine D. Brunner et al.
NATURE (2014)
The role of iron and reactive oxygen species in cell death
Scott J. Dixon et al.
NATURE CHEMICAL BIOLOGY (2014)
STRUCTURE AND FUNCTION OF TMEM16 PROTEINS (ANOCTAMINS)
Nicoletta Pedemonte et al.
PHYSIOLOGICAL REVIEWS (2014)
Duodenal Gastrointestinal Stromal Tumor With Epithelioid and Neural Features Mimicking a Primary Pancreas Head Neuroendocrine Tumor
Tomas Slavik et al.
PANCREAS (2014)
Anoctamin 6 Regulates C2C12 Myoblast Proliferation
Piming Zhao et al.
PLOS ONE (2014)
Anoctamin 6 differs from VRAC and VSOAC but is involved in apoptosis and supports volume regulation in the presence of Ca2+
C. A. Juul et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
Inhibition of TMEM16A Expression Suppresses Growth and Invasion in Human Colorectal Cancer Cells
Yujie Sui et al.
PLOS ONE (2014)
Role of anoctamins in cancer and apoptosis
Podchanart Wanitchakool et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC
Felizia K. Voss et al.
SCIENCE (2014)
ESCRT Machinery Is Required for Plasma Membrane Repair
Ana Joaquina Jimenez et al.
SCIENCE (2014)
ANO1 as a marker of oral squamous cell carcinoma and silencing ANO1 suppresses migration of human SCC-25 cells
Yadong Li et al.
MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL (2014)
The Ca2+-activated Cl- channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesis
Zhiqiang Qu et al.
CANCER MEDICINE (2014)
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
Hua Yu et al.
NATURE REVIEWS CANCER (2014)
Regulated cell death and inflammation: an auto-amplification loop causes organ failure
Andreas Linkermann et al.
NATURE REVIEWS IMMUNOLOGY (2014)
TMEM16F is a component of a Ca2+-activated Cl- channel but not a volume-sensitive outwardly rectifying Cl- channel
Takahiro Shimizu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2013)
Control of TMEM16A by INO-4995 and other inositolphosphates
Yuemin Tian et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
DOG1 Regulates Growth and IGFBP5 in Gastrointestinal Stromal Tumors
Susanne Simon et al.
CANCER RESEARCH (2013)
Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells
Seog-Young Kim et al.
CELLULAR SIGNALLING (2013)
Anticancer Effects of Niclosamide in Human Glioblastoma
Anja Wieland et al.
CLINICAL CANCER RESEARCH (2013)
Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells
Shanshan Pei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
DOG1 immunoreactivity in uterine leiomyosarcomas
Shatrughan P. Sah et al.
JOURNAL OF CLINICAL PATHOLOGY (2013)
TMEM16F (Anoctamin 6), an anion channel of delayed Ca2+ activation
Soren Grubb et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
CrossTalk proposal: Cell volume changes are an essential step in the cell death machinery
Florian Lang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
TMEM16A alternative splicing coordination in breast cancer
Ifeoma Ubby et al.
MOLECULAR CANCER (2013)
The role of TMEM16A (ANO1) and TMEM16F (ANO6) in cell migration
K. S. Jacobsen et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2013)
Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling
Adrian Britschgi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Activation of the Cl- Channel ANO1 by Localized Calcium Signals in Nociceptive Sensory Neurons Requires Coupling with the IP3 Receptor
Xin Jin et al.
SCIENCE SIGNALING (2013)
Inhibition of cell proliferation by a selective inhibitor of the Ca2+-activated Cl- channel, Ano1
Amelia Mazzone et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Inhibition of Ca2+-activated Cl- channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma
Wen Liu et al.
CANCER LETTERS (2012)
TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
Umamaheswar Duvvuri et al.
CANCER RESEARCH (2012)
TMEM16F Forms a Ca2+-Activated Cation Channel Required for Lipid Scrambling in Platelets during Blood Coagulation
Huanghe Yang et al.
CELL (2012)
Downregulation of TMEM16A Calcium-Activated Chloride Channel Contributes to Cerebrovascular Remodeling During Hypertension by Promoting Basilar Smooth Muscle Cell Proliferation
Mi Wang et al.
CIRCULATION (2012)
Expression and function of epithelial anoctamins
Karl Kunzelmann et al.
EXPERIMENTAL PHYSIOLOGY (2012)
Discovered on gastrointestinal stromal tumours 1 (DOG1) expression in non-gastrointestinal stromal tumour (GIST) neoplasms
Jessica Hemminger et al.
HISTOPATHOLOGY (2012)
Discovered on gastrointestinal stromal tumour 1 (DOG1): a useful immunohistochemical marker for diagnosing chondroblastoma
Hana Akpalo et al.
HISTOPATHOLOGY (2012)
Anoctamins are a family of Ca2+-activated Cl- channels
Yuemin Tian et al.
JOURNAL OF CELL SCIENCE (2012)
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia
Paolo Scudieri et al.
JOURNAL OF PHYSIOLOGY-LONDON (2012)
DOG1: a novel marker of salivary acinar and intercalated duct differentiation
Jacinthe Chenevert et al.
MODERN PATHOLOGY (2012)
Yeast Ist2 Recruits the Endoplasmic Reticulum to the Plasma Membrane and Creates a Ribosome-Free Membrane Microcompartment
Wendelin Wolf et al.
PLOS ONE (2012)
Enhanced Expression of ANO1 in Head and Neck Squamous Cell Carcinoma Causes Cell Migration and Correlates with Poor Prognosis
Christian Ruiz et al.
PLOS ONE (2012)
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction
Fen Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Niflumic Acid Inhibits Goblet Cell Degranulation in a Guinea Pig Asthma Model
Mitsuko Kondo et al.
ALLERGOLOGY INTERNATIONAL (2012)
DOG1 Antibody Is a Highly Sensitive and Specific Marker for Gastrointestinal Stromal Tumors in Cytology Cell Blocks
Dick G. Hwang et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2011)
Ano1 as a regulator of proliferation
Jennifer E. Stanich et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)
KIT-Negative Gastrointestinal Stromal Tumor of the Abdominal Soft Tissue: A Clinicopathologic and Genetic Study of 10 Cases
Hidetaka Yamamoto et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2011)
F508del-CFTR increases intracellular Ca2+ signaling that causes enhanced calcium-dependent Cl- conductance in cystic fibrosis
Joana Raquel Martins et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2011)
Role of the Ca2+-activated Cl- channels bestrophin and anoctamin in epithelial cells
Karl Kunzelmann et al.
BIOLOGICAL CHEMISTRY (2011)
DOG1 Utility in Diagnosing Gastrointestinal Stromal Tumors on Fine-Needle Arspiration
Nazneen Fatima et al.
CANCER CYTOPATHOLOGY (2011)
Antihelminth Compound Niclosamide Downregulates Wnt Signaling and Elicits Antitumor Responses in Tumors with Activating APC Mutations
Takuya Osada et al.
CANCER RESEARCH (2011)
Activation of the basolateral membrane Cl- conductance essential for electrogenic K+ secretion suppresses electrogenic Cl- secretion
Quanhua He et al.
EXPERIMENTAL PHYSIOLOGY (2011)
Calmodulin-dependent activation of the epithelial calcium-dependent chloride channel TMEM16A
Yuemin Tian et al.
FASEB JOURNAL (2011)
Discovered on gastrointestinal stromal tumor 1 (DOG1) is expressed in pancreatic centroacinar cells and in solid-pseudopapillary neoplasms-novel evidence for a histogenetic relationship
Frank Bergmann et al.
HUMAN PATHOLOGY (2011)
DOG1 and PKC-θ are useful in the diagnosis of KIT-negative gastrointestinal stromal tumors
Gu-Hyun Kang et al.
MODERN PATHOLOGY (2011)
Anoctamins
Karl Kunzelmann et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2011)
Anoctamin 6 is an essential component of the outwardly rectifying chloride channel
Joana Raquel Martins et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Anti-Cancer Effect of Bee Venom in Prostate Cancer Cells Through Activation of Caspase Pathway Via Inactivation of NF-κB
Mi Hee Park et al.
PROSTATE (2011)
The Utility of Discovered on Gastrointestinal Stromal Tumor 1 (DOG1) Antibody in Surgical Pathology-the GIST of It
Cheng-Han Lee et al.
ADVANCES IN ANATOMIC PATHOLOGY (2010)
Recessive Mutations in the Putative Calcium-Activated Chloride Channel Anoctamin 5 Cause Proximal LGMD2L and Distal MMD3 Muscular Dystrophies
Veronique Bolduc et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2010)
ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines
C. Ayoub et al.
BRITISH JOURNAL OF CANCER (2010)
New gene expressed in prostate: a potential target for T cell-mediated prostate cancer immunotherapy
Vittore Cereda et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2010)
Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF-κB Pathway and Generation of Reactive Oxygen Species
Yanli Jin et al.
CANCER RESEARCH (2010)
Chemistry and biochemistry of lipid peroxidation products
F. Gueraud et al.
FREE RADICAL RESEARCH (2010)
DOG1 and CD117 are the antibodies of choice in the diagnosis of gastrointestinal stromal tumours
Marco Novelli et al.
HISTOPATHOLOGY (2010)
Specificity of DOG1 (K9 clone) and protein kinase C theta (clone 27) as immunohistochemical markers of gastrointestinal stromal tumour
Newton A. C. S. Wong et al.
HISTOPATHOLOGY (2010)
Gastrointestinal stromal tumor and gastric adenocarcinoma collision tumors
Britta Kleist et al.
HUMAN PATHOLOGY (2010)
Expression and Function of Epithelial Anoctamins
Rainer Schreiber et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel
Rene Barro-Soria et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2010)
Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway
Xiaomei Ren et al.
ACS MEDICINAL CHEMISTRY LETTERS (2010)
Monoclonal Antibody DOG1.1 Shows Higher Sensitivity Than KIT in the Diagnosis of Gastrointestinal Stromal Tumors, Including Unusual Subtypes
Bernadette Liegl et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2009)
DOG1 Antibody in the Differential Diagnosis of Gastrointestinal Stromal Tumors A Study of 1840 Cases
Markku Miettinen et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2009)
TMEM16 Proteins Produce Volume-regulated Chloride Currents That Are Reduced in Mice Lacking TMEM16A
Joana Almaca et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Autonomous Notch Signal Pathway Is Activated by Baicalin and Baicalein But Is Suppressed by Niclosamide in K562 Cells
An-Ming Wang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2009)
Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels
H. Criss Hartzell et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
Bestrophin 1 Promotes Epithelial-to-mesenchymal Transition of Renal Collecting Duct Cells
Fadi Aldehni et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
Physiology of Cell Volume Regulation in Vertebrates
Else K. Hoffmann et al.
PHYSIOLOGICAL REVIEWS (2009)
Pancreatic Expression of DOG1 A Novel Gastrointestinal Stromal Tumor (GIST) Biomarker
Carmen Ardeleanu et al.
APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY (2009)
Bestrophin-1 Enables Ca2+-activated Cl- Conductance in Epithelia
Rene Barro Soria et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors
Inigo Espinosa et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2008)
Prognostic impact of array-based genomic profiles in esophageal squamous cell cancer
Ana Carneiro et al.
BMC CANCER (2008)
Topology of NGEP, a prostate-specific cell: Cell junction protein widely expressed in many cancers of different grade level
Sudipto Das et al.
CANCER RESEARCH (2008)
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit
Bjoern Christian Schroeder et al.
CELL (2008)
Mutation assay of the novel gene DOG1 in gastrointestinal stromal tumors (GISTs)
Shigeharu Miwa et al.
JOURNAL OF GASTROENTEROLOGY (2008)
TMEM16A confers receptor-activated calcium-dependent chloride conductance
Young Duk Yang et al.
NATURE (2008)
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity
Antonella Caputo et al.
SCIENCE (2008)
Impaired activity of volume-sensitive Cl- channel is involved in cisplatin resistance of cancer cells
Elbert L. Lee et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2007)
NGEP, a prostate-specific plasma membrane protein that promotes the association of LNCaP cells
Sudipto Das et al.
CANCER RESEARCH (2007)
Calcium microdomains in regulated exocytosis
Martin Oheim et al.
CELL CALCIUM (2006)
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate
Dunyaporn Trachootham et al.
CANCER CELL (2006)
Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display
A Carles et al.
ONCOGENE (2006)
Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death
Y. Okada et al.
JOURNAL OF MEMBRANE BIOLOGY (2006)
Structure and function of CLCA proteins
ME Loewen et al.
PHYSIOLOGICAL REVIEWS (2005)
Ca2+ signaling, intracellular pH and cell volume in cell proliferation
R Schreiber
JOURNAL OF MEMBRANE BIOLOGY (2005)
Ion channels and cancer
K Kunzelmann
JOURNAL OF MEMBRANE BIOLOGY (2005)
Ca2+- and volume-sensitive chloride currents are differentially regulated by agonists and store-operated Ca2+ entry
A Zholos et al.
JOURNAL OF GENERAL PHYSIOLOGY (2005)
Calcium-activated chloride channels
C Hartzell et al.
ANNUAL REVIEW OF PHYSIOLOGY (2005)
Opinion - Regulated exocytosis: new organelles for non-secretory purposes
E Chieregatti et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate
TK Bera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Bcl-2-dependent modulation of swelling-activated Cl- current and ClC-3 expression in human prostate cancer epithelial cells
L Lemonnier et al.
CANCER RESEARCH (2004)
The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status
RB West et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
S Dolma et al.
CANCER CELL (2003)
A congenital mutation of the novel gene LRRC8 causes agammaglobulinemia in humans
A Sawada et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Modulation of the Ras/Raf/MEK/ERK pathway by Ca2+, and calmodulin
N Agell et al.
CELLULAR SIGNALLING (2002)
IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro
LJV Galietta et al.
JOURNAL OF IMMUNOLOGY (2002)
Ca2+ modulation of volume-regulated anion channels:: evidence for colocalization with store-operated channels
L Lemonnier et al.
FASEB JOURNAL (2001)
A src-like kinase activates outwardly rectifying chloride channels in CFTR-defective lymphocytes
A Lepple-Wienhues et al.
FASEB JOURNAL (2001)
分享论文
