4.6 Review

A walk through tau therapeutic strategies

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Methylene blue and Alzheimer's disease

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Tau exon 10 alternative splicing and tauopathies

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EMBO JOURNAL (2007)

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Extracellular tau is toxic to neuronal cells

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FEBS LETTERS (2006)

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FEBS LETTERS (2006)

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Incidence and predictors of seizures in patients with Alzheimer's disease

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Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and α-synuclein

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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

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Tau suppression in a neurodegenerative mouse model improves memory function

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SCIENCE (2005)

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Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins

S Taniguchi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Tau aggregation is driven by a transition from random coil to beta sheet structure

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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)

Review Biochemistry & Molecular Biology

Tau protein as a differential biomarker of tauopathies

N Sergeant et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)

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Staging of argyrophilic grains: An age-associated tauopathy

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JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)

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Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury

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EXPERIMENTAL NEUROLOGY (2004)

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Nitration of tau protein is linked to neurodegeneration in tauopathies

T Horiguchi et al.

AMERICAN JOURNAL OF PATHOLOGY (2003)

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Association of phosphorylation site of tau protein with neuronal apoptosis in Alzheimer's disease

K Kobayashi et al.

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Tau could protect DNA double helix structure

Q Hua et al.

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Office of rare diseases neuropathologic criteria for corticobasal degeneration

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Natively unfolded proteins: A point where biology waits for physics

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Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease

F Liu et al.

FEBS LETTERS (2002)

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In vitro assembly of tau protein:: Mapping the regions involved in filament formation

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ANNUAL REVIEW OF NEUROSCIENCE (2001)

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Tau protein isoforms, phosphorylation and role in neurodegenerative disorders

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BRAIN RESEARCH REVIEWS (2000)

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Neural substrates of spatial and temporal disorientation in Alzheimer's disease

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ACTA NEUROPATHOLOGICA (2000)

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Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming β structure

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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

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Clinical validity of Braak neuropathological staging in the oldest-old

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