期刊
ANIMAL GENETICS
卷 48, 期 2, 页码 175-181出版社
WILEY
DOI: 10.1111/age.12520
关键词
miR-196a; miR-196b-5p; miRNA-seq; Wannanhua pig; Yorkshire pig
资金
- Dean Young Innovation Fund Projects [16B0407]
- National Natural Science Foundation of China [31371258]
- Anhui International Technology Cooperation Plan Project [1503062014]
- Anhui Swine Industry Technology System Project [AHCYTX-06-10]
- Anhui Modern Agricultural Project for Pig Industry [13000101]
- Anhui Finance Project for Animal Husbandry Development [14225001]
- Maanshan Science and Technology Plan Project [15001727]
- Anhui Academy of Agricultural Sciences President Innovation Fund Project for Outstanding Youth [13B0405]
- Anhui Academy of Agricultural Science and Technology Innovation Team Building Project [13C0405]
Intramuscular fat (IMF) is one of the fat traits that has economic importance in the pork industry. Longissimus dorsi muscle contains IMF and is suitable for studying adipogenesis. To discover further potential regulatory miRNAs that may influence adipogenesis, we analyzed miRNA in the longissimus dorsi muscle of Yorkshire (YY, lean-type) and Chinese Wannanhua (WH, fatty) pigs using miRNA sequencing (miRNA-seq). From this dataset, we identified 598 unique miRNAs comprising 325 pre-miRNAs and 273 novel pre-miRNAs through comparison with known miRNAs in miRBase version 21. We found 42 miRNAs including nine up-and 33 down-regulated between the YY and WH pigs. Moreover, we found two miRNAs, miR-196a/b (miR-196a, miR-196b-5p), that had the highest level of expression in WH pigs, and miR-196a/b may influence porcine adipogenesis in longissimus dorsi muscle through an adipocytokine signaling pathway.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据