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TRENDS IN IMMUNOLOGY (2011)
Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors
Elena Alberdi et al.
CELL CALCIUM (2010)
Global estimates of the prevalence of diabetes for 2010 and 2030
J. E. Shaw et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2010)
Regulation of mitochondrial biogenesis
Francois R. Jornayvaz et al.
ESSAYS IN BIOCHEMISTRY: MITOCHONDRIAL FUNCTION (2010)
New insights into the role of mitochondria in aging: mitochondrial dynamics and more
Arnold Y. Seo et al.
JOURNAL OF CELL SCIENCE (2010)
Reperfusion and Neurovascular Dysfunction in Stroke: from Basic Mechanisms to Potential Strategies for Neuroprotection
Joo Eun Jung et al.
MOLECULAR NEUROBIOLOGY (2010)
Systemic inflammation and disease progression in Alzheimer disease
C. Holmes et al.
NEUROLOGY (2009)
SUSTAINED EXPRESSION OF INTERLEUKIN-1β IN MOUSE HIPPOCAMPUS IMPAIRS SPATIAL MEMORY
A. H. Moore et al.
NEUROSCIENCE (2009)
Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans
Jeremy M. Van Raamsdonk et al.
PLOS GENETICS (2009)
Cardioprotective effects of propofol in isolated ischemia-reperfused guinea pig hearts:: role of KATP channels and GSK-3β
Noriko Kamada et al.
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE (2008)
Mitochondrial biogenesis and healthy aging
Guillermo Lopez-Lluch et al.
EXPERIMENTAL GERONTOLOGY (2008)
The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective
Solomon S. Shaftel et al.
JOURNAL OF NEUROINFLAMMATION (2008)
Association between interleukin-6 and lower extremity function after hip fracture - The role of muscle mass and strength
Ram R. Miller et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2008)
General anesthetics activate a nociceptive ion channel to enhance pain and inflammation
Jose A. Matta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
P. Hemachandra Reddy et al.
TRENDS IN MOLECULAR MEDICINE (2008)
Inflammaging as a major characteristic of old people: Can it be prevented or cured?
Claudio Franceschi
NUTRITION REVIEWS (2007)
Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans
Shane L. Rea et al.
PLOS BIOLOGY (2007)
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
V. Petrilli et al.
CELL DEATH AND DIFFERENTIATION (2007)
Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKα
Wan Qiang et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2007)
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
Sibylle Jaeger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Detection of potassium currents and regulation of multidrug resistance by potassium channels in human gastric cancer cells
Ying Han et al.
CELL BIOLOGY INTERNATIONAL (2007)
Systemic markers of inflammation and cognitive decline in old age
Miranda T. Schram et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2007)
Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis
Richard M. Reznick et al.
CELL METABOLISM (2007)
Expression of mitochondrial biogenesis-signaling factors in brown adipocytes is influenced specifically by 17 beta-estradiol, testosterone, and progesterone
S. Rodriguez-Cuenca et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) reduces afterhyperpolarizing current in hippocampal CA1 neurons
Dorte Strobaek et al.
MOLECULAR PHARMACOLOGY (2006)
Persistent changes in interleukin-6 and lower extremity function following hip fracture
Ram R. Miller et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2006)
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
Y Kraytsberg et al.
NATURE GENETICS (2006)
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
DM Bautista et al.
CELL (2006)
Expanding insights of mitochondrial dysfunction in Parkinson's disease
PM Abou-Sleiman et al.
NATURE REVIEWS NEUROSCIENCE (2006)
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
G López-Lluch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Expression of delayed rectifier potassium channels and their possible roles in proliferation of human gastric cancer cells
M Lan et al.
CANCER BIOLOGY & THERAPY (2005)
Age-associated decline in mitochondrial respiration and electron transport in Drosophila melanogaster
M Ferguson et al.
BIOCHEMICAL JOURNAL (2005)
Alternative splicing switches the divalent cation selectivity of TRPM3 channels
J Oberwinkler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Role of voltage-gated potassium channels in cancer
LA Pardo et al.
JOURNAL OF MEMBRANE BIOLOGY (2005)
Metabolic control through the PGC-1 family of transcription coactivators
JD Lin et al.
CELL METABOLISM (2005)
Mechanisms of disease - Inflammation, atherosclerosis, and coronary artery disease
GK Hansson
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing
K Nagata et al.
JOURNAL OF NEUROSCIENCE (2005)
IL-10, IL-6, and TNF-α:: Central factors in the altered cytokine network of uremia -: The good, the bad, and the ugly
P Stenvinkel et al.
KIDNEY INTERNATIONAL (2005)
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
JT Rodgers et al.
NATURE (2005)
IL-6-induced skeletal muscle atrophy
F Haddad et al.
JOURNAL OF APPLIED PHYSIOLOGY (2005)
Inflammatory proteins in plasma and the risk of dementia - The Rotterdam study
MJ Engelhart et al.
ARCHIVES OF NEUROLOGY (2004)
Functional characterization of the L-type Ca2+ channel Cav1.4α1 from mouse retina
L Baumann et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)
Binding specificity of sea anemone toxins to Nav1.1-1.6 sodium channels -: Unexpected contributions from differences in the IV/S3-S4 outer loop
JS Oliveira et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
VDAC: The channel at the interface between mitochondria and the cytosol
M Colombini
MOLECULAR AND CELLULAR BIOCHEMISTRY (2004)
Maldaptation of the link between inflammation and bone turnover may be a key determinant of osteoporosis
AJ Yun et al.
MEDICAL HYPOTHESES (2004)
Ink4a/Arf expression is a biomarker of aging
J Krishnamurthty et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Testosterone is a potent inhibitor of L-type Ca2+ channels
JL Scragg et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Inflammatory markers and onset of cardiovascular events - Results from the Health ABC study
M Cesari et al.
CIRCULATION (2003)
Calorie restriction and aging: review of the literature and implications for studies in humans
LK Heilbronn et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2003)
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
SE Kahn
DIABETOLOGIA (2003)
Cytokines and cognition - The case for a head-to-toe inflammatory paradigm
CJ Wilson et al.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2002)
Interleukin-6 and risk of cognitive decline - MacArthur studies of successful aging
JD Weaver et al.
NEUROLOGY (2002)
Ageing muscle:: clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function
G Fayet et al.
NEUROMUSCULAR DISORDERS (2002)
Relationship of interleukin-6 and tumor necrosis factor-α with muscle mass and muscle strength in elderly men and women:: The health ABC study
M Visser et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2002)
Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria
M López-Torres et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Endothelial cell senescence in human atherosclerosis - Role of telomere in endothelial dysfunction
T Minamino et al.
CIRCULATION (2002)
Inflammation and stroke -: The Leiden 85-plus study
E van Exel et al.
STROKE (2002)
Ageing is associated with a decrease in the number of sarcolemmal ATP-sensitive K+ channels in a gender-dependent manner
HJ Ranki et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2002)
X-ray structure of a CIC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
R Dutzler et al.
NATURE (2002)
Aging, ion channel expression, and vascular function
L Toro et al.
VASCULAR PHARMACOLOGY (2002)
Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2
VG Shakkottai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Increased calcium vulnerability of senescent cardiac mitochondria: protective role for a mitochondrial potassium channel opener
A Jahangir et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2001)
Mitochondrial dysfunction in cardiac disease: Ischemia-reperfusion, aging, and heart failure
EJ Lesnefsky et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Cloning and functional expression of a liver isoform of the small conductance Ca2+-activated K+ channel SK3
ET Barfod et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2001)
Estrogen induces the Akt-dependent activation of endothelial nitric-oxide synthase in vascular endothelial cells
K Hisamoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Specific neosaxitoxin interactions with the Na+ channel outer vestibule determined by mutant cycle analysis
JL Penzotti et al.
BIOPHYSICAL JOURNAL (2001)
Reduction of inflammatory response in the mouse brain with adenoviral-mediated transforming growth factor-β1 expression
L Pang et al.
STROKE (2001)
Bone mineral density in acute stroke patients - Low bone mineral density may predict first stroke in women
L Jorgensen et al.
STROKE (2001)
Novel ω-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes
RJ Lewis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Nicotine is a potent blocker of the cardiac A-type K+ channels -: Effects on cloned Kv4.3 channels and native transient outward current
HZ Wang et al.
CIRCULATION (2000)
Progression of aortic calcification is associated with metacarpal bone loss during menopause - A population-based longitudinal study
AE Hak et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)
Isoflurane, but not halothane, induces protection of human myocardium via adenosine A1 receptors and adenosine triphosphate-sensitive potassium channels
AK Roscoe et al.
ANESTHESIOLOGY (2000)
Inflammation and Alzheimer's disease
H Akiyama et al.
NEUROBIOLOGY OF AGING (2000)
Increased plasma levels of interleukin-1, interleukin-6 and α-1-antichymotrypsin in patients with Alzheimer's disease:: peripheral inflammation or signals from the brain?
F Licastro et al.
JOURNAL OF NEUROIMMUNOLOGY (2000)
Distinction among neuronal subtypes of voltage-activated sodium channels by mu-conotoxin PIIIA
P Safo et al.
JOURNAL OF NEUROSCIENCE (2000)
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