期刊
TOXINS
卷 11, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/toxins11020078
关键词
mycotoxins; occupational exposure; swine production; biomonitoring; mycotoxins mixture
资金
- Instituto Politecnico de Lisboa, Lisbon, Portugal: Project Bacterial Bioburden assessment in the context of occupational exposure and animal health of swine productions (IPL/2016/BBIOR_ESTeSL)
- FCT-Fundacao para Ciencia e Tecnologia: Project EXPOsE - Establishing protocols to assess occupational exposure to microbiota in clinical settings [02/SAICT/2016, 23222]
Swine production workers are exposed simultaneously to multiple contaminants. Occupational exposure to aflatoxin B-1 (AFB(1)) in Portuguese swine production farms has already been reported. However, besides AFB(1), data regarding fungal contamination showed that exposure to other mycotoxins could be expected in this setting. The present study aimed to characterize the occupational exposure to multiple mycotoxins of swine production workers. To provide a broad view on the burden of contamination by mycotoxins and the workers' exposure, biological (urine) samples from workers (n = 25) and 38 environmental samples (air samples, n = 23; litter samples, n = 5; feed samples, n = 10) were collected. The mycotoxins biomarkers detected in the urine samples of the workers group were the deoxynivalenol-glucuronic acid conjugate (60%), aflatoxin M-1 (16%), enniatin B (4%), citrinin (8%), dihydrocitrinone (12%) and ochratoxin A (80%). Results of the control group followed the same pattern, but in general with a lower number of quantifiable results (
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