4.8 Article

Synthesis of Functionalized Dihydrobenzofurans by Direct Aryl C-O Bond Formation under Mild Conditions

期刊

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 55, 期 38, 页码 11625-11628

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201605648

关键词

copper; cyclization; fused-ring systems; iodonium salts; oxygen heterocycles

资金

  1. NSF [CHE-1463819]
  2. Amgen
  3. Eli Lilly
  4. NIH Shared Instrumentation Grant (SIG) [1S10OD012077-01A1]
  5. Direct For Mathematical & Physical Scien [1463819] Funding Source: National Science Foundation
  6. Division Of Chemistry [1463819] Funding Source: National Science Foundation

向作者/读者索取更多资源

A method for the synthesis of dihydrobenzofurans by a direct aryl C-O bond formation is described. A mechanistic pathway for the reaction, distinct from previously described similar transformations, allows for mild reaction conditions that are expected to be compatible with functionalized substrates.

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