期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 55, 期 32, 页码 9437-9440出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201603899
关键词
electrochemistry; green chemistry; heterocycles; N-N coupling; pyrazolidin-3,5-diones
资金
- DFG by the Excellence Initiative by the Graduate School Materials Science in Mainz [GSC 266]
Pyrazolidin-3,5-diones are important motifs in heterocyclic chemistry and are of high interest for pharmaceutical applications. In classic organic synthesis, the hydrazinic moiety is installed through condensation using the corresponding hydrazine building blocks. However, most N,N'-diaryl hydrazines are toxic and require upstream preparation owing to their low commercial availability. We present an alternative and sustainable synthetic approach to pyrazolidin-3,5-diones that employs readily accessible dianilides as precursors, which are anodically converted to furnish the N-N bond. The electroconversion is conducted in a simple undivided cell under constant-current conditions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据