期刊
WORLD NEUROSURGERY
卷 122, 期 -, 页码 417-423出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.wneu.2018.11.011
关键词
Long-term survival; Pituitary carcinoma; Pituitary neoplasm transformation
资金
- University of Alabama Department of Neurosurgery
BACKGROUND: Pituitary carcinomas are rare and aggressive neoplasms that despite current treatment regimens continue to have a poor prognosis. Adrenocorticotrophic hormone pituitary tumors have been shown to alter their clinical manifestations with conversion to Cushing disease and silent types. CASE DESCRIPTION: The purpose of this paper is to present the first documented case of an adrenocorticotrophic hormone-secreting pituitary adenoma with Cushing disease that differentiated into a silent corticotroph pituitary carcinoma with metastases to distant sites in the central nervous system. CONCLUSIONS: This patient was later treated with radiotherapy, temozolo-mide, and bevacizumab, with 8 years of progression-free survival.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据