期刊
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
卷 55, 期 42, 页码 13240-13243出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201606195
关键词
allenes; cycloaddition; heterocycles; rhodium; synthetic methods
资金
- NIH [1R01GM111412-01, RR08389-01, P41GM103399, S10RR08438, S10RR029220]
- NSF [1254397, CHE-9208463, CHE-9629688, BIR-0214394]
- Direct For Mathematical & Physical Scien
- Division Of Chemistry [1254397] Funding Source: National Science Foundation
A tandem allene aziridination/[4+3]/reduction sequence converts simple homoallenic sulfamates into densely functionalized aminated cycloheptenes, where the relative stereochemistry at five contiguous asymmetric centers can be controlled through the choice of the solvent and the reductant. The products resulting from this chemistry can be readily transformed into complex molecular scaffolds which contain up to seven contiguous stereocenters.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据