4.8 Article

Enantioselective Alkynylation of Isatin Derivatives Using a Chiral Phase-Transfer/Transition-Metal Hybrid Catalyst System

期刊

ACS CATALYSIS
卷 9, 期 3, 页码 2395-2399

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acscatal.8b04949

关键词

phase-transfer catalyst; hybrid catalyst; asymmetric alkynylation; isatin; silver acetate

资金

  1. JSPS KAKENHI [JP26220803, JP17H06450]

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An enantioselective alkynylation of isatin derivatives can be realized by using a hybrid catalyst system consisting of chiral phase-transfer catalyst and transition-metal catalyst. The chiral alkynylation products can be used as versatile intermediates for further synthetic transformations.

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