期刊
JOURNAL OF FUNCTIONAL FOODS
卷 53, 期 -, 页码 286-291出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jff.2018.12.041
关键词
Whole grain; Resistant starch; Polyphenols; Gut microbiota; Principal Component Analysis; Type-2 diabetes
资金
- Ingredion Incorporated
- LSU AgCenter
- Major International (Regional) Joint Research Project of National Natural Science Foundation of China [81220108006]
This study aimed at assessing the influence of an 11 weeks intervention with a resistant starch-enriched whole grain diet (HI-RS-WG, 25% RS) compared to a WG control diet (LOW-RS-WG, 6.9% RS) on serum profile of polyphenols (PPs) in 20 Zucker Diabetic Fatty rats. Five PPs were identified and quantified in serum samples of rats belonging to both intervention groups. HI-RS-WG rats had 2.6 folds higher serum concentrations of total PPs than LOW-RS-WG rats. An explorative data reduction approach, based on the Principal Component Analysis identified two principal components related to the gut microbiota fermentation and food intake, respectively. Results showed that the abundance of hippuric acid and dihydroferulic acid in HI-RS-WG rats was explained by the stronger gut microbiota fermentation in those rats than in LOW-RS-WG rats.
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