期刊
TRENDS IN BIOTECHNOLOGY
卷 37, 期 2, 页码 181-197出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2018.11.002
关键词
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资金
- US-UK Fulbright award
- Imperial College London
- BBSRC [BB/R01602X/1]
- Biotechnology and Biological Sciences Research Council (BBSRC) [BIV-17-ledesma-amaro-C1net]
- BBSRC [BB/R01602X/1] Funding Source: UKRI
Microbial consortia have been used in biotechnology processes, including fermentation, waste treatment, and agriculture, for millennia. Today, synthetic biologists are increasingly engineering microbial consortia for diverse applications, including the bioproduction of medicines, biofuels, and biomaterials from inexpensive carbon sources. An improved understanding of natural microbial ecosystems, and the development of new tools to construct synthetic consortia and program their behaviors, will vastly expand the functions that can be performed by communities of interacting microorganisms. Here, we review recent advancements in synthetic biology tools and approaches to engineer synthetic microbial consortia, discuss ongoing and emerging efforts to apply consortia for various biotechnological applications, and suggest future applications.
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