期刊
TECHNOLOGY IN CANCER RESEARCH & TREATMENT
卷 18, 期 -, 页码 -出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1533033818821421
关键词
breast cancer; diagnostics; exosome; miRNA; protein
类别
资金
- Doctoral Scientific Research Foundation [201601412]
- Natural Science Foundation of Liaoning Province [20180550488]
- Excellent Talent Fund of Liaoning Province Cancer Hospital
Currently, despite the advances in individualized treatment, breast cancer still remains the deadliest form of cancer in women. Diagnostic, prognostic, and therapy-predictive methods are mainly based on the evaluation of tumor tissue samples and are aimed to improve the overall therapeutic level. Therefore, the exploration of a series of circulating biomarkers, which serve as the information source of tumors and could be obtained by peripheral blood samples, represents a high field of interest. Apart from classical biomarkers, exosomes, which are nanovesicles, are emerging as an accessible and efficient source of cell information. The purpose of this review is to summarize the peculiarities of the presently available breast cancer exosomal biomarkers; the review also provides the prediction of a multitude of potential target genes of exosomal microRNAs using 4 databases.
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