A perspective on biogenic synthesis of platinum nanoparticles and their biomedical applications

In recent era, the interest on inorganic nanoparticles is augmenting due to their engrossing and uncanny properties. Among them, platinum nanoparticles (PtNPs) are highly remarkable owing to their intrinsic physicochemical and biological properties making them an effective candidate towards catalytic and biomedical applications. Nevertheless, conventional physical and chemical methodologies of PtNPs synthesis are among the mast prevalent protocols to synthesize PtNPs of desired shape and size. However, the above methods create notable concern to health and environment due to the use of harsh and toxic chemicals as well as violent reaction conditions. Hence, an economic, eco-friendly, non-toxic and sustainable route for the synthesis of PtNPs is the need of the hour to circumvent the shortcomings associated with conventional methodologies. In this aspect, the approach of green synthesis has lightened up the way for the environmentally benign synthesis of PtNPs. Interestingly, this review focuses chiefly on the green synthesis of PtNPs from various biological entities such as microorganisms, plants, seaweeds and other innovative miscellaneous protocols. Furthermore, it also summarizes the potential biomedical applications of PtNPs especially as an antibacterial agent and their role as nanomedicine. Overall, the emerging biogenic synthesis of PtNPs makes it feasible to foresee more promising biomedical outcomes in the upcoming future. (C) 2018 Elsevier B.V. All rights reserved.