相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape
Daniel T. Infield et al.
JOURNAL OF GENERAL PHYSIOLOGY (2018)
SWISS-MODEL: homology modelling of protein structures and complexes
Andrew Waterhouse et al.
NUCLEIC ACIDS RESEARCH (2018)
Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors
Tania Chernov-Rogan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
The voltage-gated sodium channel EF-hands form an interaction with the III-IV linker that is disturbed by disease-causing mutations
Bernd R. Gardill et al.
SCIENTIFIC REPORTS (2018)
cisTEM, user friendly software for single-particle image processing
Timothy Grant et al.
ELIFE (2018)
Na(v)1.7 inhibitors for the treatment of chronic pain
Steven J. McKerrall et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)
Membrane protein structural biology in the era of single particle cryo-EM
Yifan Cheng
CURRENT OPINION IN STRUCTURAL BIOLOGY (2018)
Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1
Xiaojing Pan et al.
SCIENCE (2018)
Structural basis for the modulation of voltage-gated sodium channels by animal toxins
Huaizong Shen et al.
SCIENCE (2018)
Selective NaV1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain
Girish Bankar et al.
CELL REPORTS (2018)
Insensitivity to Pain upon Adult-Onset Deletion of Nav1.7 or Its Blockade with Selective Inhibitors
Shannon D. Shields et al.
JOURNAL OF NEUROSCIENCE (2018)
Mechanisms of noncovalent β subunit regulation of NaV channel gating
Wandi Zhu et al.
JOURNAL OF GENERAL PHYSIOLOGY (2017)
Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution
Huaizong Shen et al.
SCIENCE (2017)
Structure-based assessment of disease-related mutations in human voltage-gated sodium channels
Weiyun Huang et al.
PROTEIN & CELL (2017)
Depolarization of the conductance-voltage relationship in the NaV1.5 mutant, E1784K, is due to altered fast inactivation
Colin H. Peters et al.
PLOS ONE (2017)
Structure of the Nav1.4-β1 Complex from Electric Eel
Zhen Yan et al.
CELL (2017)
The hitchhiker's guide to the voltage-gated sodium channel galaxy
Christopher A. Ahern et al.
JOURNAL OF GENERAL PHYSIOLOGY (2016)
Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana
Jiangtao Guo et al.
NATURE (2016)
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
Jeremiah D. Osteen et al.
NATURE (2016)
Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana
Alexander F. Kintzer et al.
NATURE (2016)
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
Jianping Wu et al.
NATURE (2016)
Binary architecture of the Nav1.2-β2 signaling complex
Samir Das et al.
ELIFE (2016)
Benchmarking the stability of human detergent-solubilised voltage-gated sodium channels for structural studies using eel as a reference
Daria Slowik et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist
Shivani Ahuja et al.
SCIENCE (2015)
Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains
Stephan A. Pless et al.
JOURNAL OF GENERAL PHYSIOLOGY (2014)
Impaired Action Potential Initiation in GABAergic Interneurons Causes Hyperexcitable Networks in an Epileptic Mouse Model Carrying a Human NaV1.1 Mutation
Ulrike B. S. Hedrich et al.
JOURNAL OF NEUROSCIENCE (2014)
X-ray crystal structure of voltage-gated proton channel
Kohei Takeshita et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Evolutionarily conserved intracellular gate of voltage-dependent sodium channels
Kevin Oelstrom et al.
NATURE COMMUNICATIONS (2014)
S1-S3 counter charges in the voltage sensor module of a mammalian sodium channel regulate fast inactivation
James R. Groome et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels
Deborah L. Capes et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
One number does not fit all: Mapping local variations in resolution in cryo-EM reconstructions
Giovanni Cardone et al.
JOURNAL OF STRUCTURAL BIOLOGY (2013)
Crystallographic insights into sodium-channel modulation by the β4 subunit
John Gilchrist et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channel
Marcel P. Goldschen-Ohm et al.
NATURE COMMUNICATIONS (2013)
Structural Insights into Antibody Sequestering and Neutralizing of Na+ Channel α-Type Modulator from Old World Scorpion Venom
Igor P. Fabrichny et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Gating pore currents and the resting state of Nav1.4 voltage sensor domains
Pascal Gosselin-Badaroudine et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Spider-venom peptides that target voltage-gated sodium channels: Pharmacological tools and potential therapeutic leads
Julie K. Klint et al.
TOXICON (2012)
Mapping the receptor site for α-scorpion toxins on a Na+ channel voltage sensor
Jinti Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
A Gating Charge Transfer Center in Voltage Sensors
Xiao Tao et al.
SCIENCE (2010)
Biophysical defects in voltage-gated sodium channels associated with long QT and Brugada syndromes
David K. Jones et al.
CHANNELS (2008)
α-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels
Fabiana V. Campos et al.
JOURNAL OF GENERAL PHYSIOLOGY (2008)
Deconstructing voltage sensor function and pharmacology in sodium channels
Frank Bosmans et al.
NATURE (2008)
Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment
Stephen B. Long et al.
NATURE (2007)
Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations
Y. P. Goldberg et al.
CLINICAL GENETICS (2007)
Gating pore current in an inherited ion channelopathy
Stanislav Sokolov et al.
NATURE (2007)
Voltage-gated sodium channel modulation by scorpion α-toxins
Frank Bosmans et al.
TOXICON (2007)
Site-3 toxins and cardiac sodium channels
Dorothy A. Hanck et al.
TOXICON (2007)
Voltage-gated ion channels and gating modifier toxins
William A. Catterall et al.
TOXICON (2007)
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
Frank H. Niesen et al.
NATURE PROTOCOLS (2007)
An SCN9A channelopathy causes congenital inability to experience pain
James J. Cox et al.
NATURE (2006)
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating
Angelika Lampert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Single-channel properties of human Na(V)1.1 and mechanism of channel dysfunction in SCN1A-associated epilepsy
CG Vanoye et al.
JOURNAL OF GENERAL PHYSIOLOGY (2006)
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels
WA Catterall et al.
PHARMACOLOGICAL REVIEWS (2005)
Sodium channel inactivation: Molecular determinants and modulation
W Ulbricht
PHYSIOLOGICAL REVIEWS (2005)
Automated electron microscope tomography using robust prediction of specimen movements
DN Mastronarde
JOURNAL OF STRUCTURAL BIOLOGY (2005)
Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements
B Chanda et al.
JOURNAL OF GENERAL PHYSIOLOGY (2004)
Molecular cloning and functional expression of the alpha-scorpion toxin BotIII:: pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels
K Benkhadir et al.
PEPTIDES (2004)
Characterization of Amm VIII from Androctonus mauretanicus mauretanicus:: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels
M Alami et al.
BIOCHEMICAL JOURNAL (2003)
Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy
PB Rosenthal et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Exploration of the functional site of a scorpion α-like toxin by site-directed mutagenesis
CG Wang et al.
BIOCHEMISTRY (2003)
Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation
B Chanda et al.
JOURNAL OF GENERAL PHYSIOLOGY (2002)
Ion conduction pore is conserved among potassium channels
Z Lu et al.
NATURE (2001)
Functional effects of two voltage-gated sodium channel mutations that cause generalized epilepsy with febrile seizures plus type 2
J Spampanato et al.
JOURNAL OF NEUROSCIENCE (2001)
Electrophysiological characterization of SCN5A mutations causing long QT (E1784K) and Brugada (R1512W and R1432G) syndromes
I Deschênes et al.
CARDIOVASCULAR RESEARCH (2000)