期刊
SCIENCE
卷 363, 期 6434, 页码 1443-+出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aav4837
关键词
-
资金
- European Research Council [281511]
- European Union Horizon 2020 grant [665385]
- European Research Council (ERC) [281511] Funding Source: European Research Council (ERC)
Grid cells with their rigid hexagonal firing fields are thought to provide an invariant metric to the hippocampal cognitive map, yet environmental geometrical features have recently been shown to distort the grid structure. Given that the hippocampal role goes beyond space, we tested the influence of nonspatial information on the grid organization. We trained rats to daily learn three new reward locations on a cheeseboard maze while recording from the medial entorhinal cortex and the hippocampal CA1 region. Many grid fields moved toward goal location, leading to long-lasting deformations of the entorhinal map. Therefore, distortions in the grid structure contribute to goal representation during both learning and recall, which demonstrates that grid cells participate in mnemonic coding and do not merely provide a simple metric of space.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据