期刊
POLYMER
卷 167, 期 -, 页码 1-12出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.polymer.2019.01.053
关键词
PVDF membrane; Surface grafting; Protein adsorption
资金
- National Natural Science Foundation of China [21574100]
- Science and Technology Plans of Tianjin [16PTSYJC00090]
- Program for Innovative Research Team in University of Tianjin [TD13-5044]
It remains a major challenge to prepare membranes with minimal protein adsorption for bio-related applications. In this work, modified polyvinylidene difluoride (PVDF) membranes having ultralow protein adsorption were prepared by grafting zwitterionic and PEGylated cross-linked polymers onto the membrane surface. The PVDF membrane was first treated with alkaline and tethered with cross-linked polyethylene glycol diacrylate (CPEGDA) via ATRP. By reacting the abundant alkene group M the periphery of CPEGDA with cystine or monomethyl PEG thiol (MPEG-SH, M = 200, 600, 2000) by thio-ene reaction, the membrane surface was tethered with high density protein repellent groups. The PVDF-g-CLPEG2000 membrane shows the best performance and its bovine serum albumin (BSA) and bovine serum fibrinogen (BFG) adsorptions can be lowered to only 1/50 and 1/40 that of the original PVDF membrane, respectively. Similar fouling tendencies were observed in the dynamic filtration process. This work addresses the significance of cross-linked grafting on altering membrane surface properties.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据